TY - JOUR AU - Tajik, Parvin AU - Zafarmand, Mohammad Hadi AU - Zwinderman, Aeilko H. AU - Mol, Ben W. AU - Bossuyt, Patrick M. PY - 2018 DA - 2018/06/28 TI - Development and evaluating multimarker models for guiding treatment decisions JO - BMC Medical Informatics and Decision Making SP - 52 VL - 18 IS - 1 AB - Despite the growing interest in developing markers for predicting treatment response and optimizing treatment decisions, an appropriate methodology to identify, combine and evaluate such markers has been slow to develop. We propose a step-by-step strategy for analysing data from existing randomised trials with the aim of identifying a multi-marker model for guiding decisions about treatment. SN - 1472-6947 UR - https://doi.org/10.1186/s12911-018-0619-5 DO - 10.1186/s12911-018-0619-5 ID - Tajik2018 ER -