Fig. 7
From: A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactions
Sensitivity of the interactions towards the perturbations in the association (kon) and dissociation (koff) rate constants for CTLA-4/Tremelimumab complex. The changes in the numbers of CTLA-4/Tremelimumab complex (a), CTLA-4/B7–1 complex (b), CTLA-4/B7–2 complex (c), CD28/B7–1 complex (d), and CD28/B7–2 complex (e) in response to the perturbations are shown