Fig. 5From: A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactionsAntibody-mediated changes in the complex formation at the synapse in the free-diffusion model: The dynamic changes in the different complexes, such as CTLA-4/antibody, CTLA-4/B7 ligands and CD28/B7 ligands, at the synapse are simulated at 10 μM and 15 μM of antibodies, ipilimumab (a, c) and tremelimumab (b, d)Back to article page