Fig. 2
From: A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactions
Complex formation in the free-diffusion model from the antibody-free simulations. The number of CD28 and CTLA-4 molecules bound to B7–1 and B7–2 at the immunological synapse, during the antibody-free simulations (a). The dynamic changes in the total numbers of CTLA-4/B7 complex, CD28/B7 complex, amount of CTLA-4 at the intra-cellular environment and the total number of CTLA-4 monomers are provided (b)