Table 5 The top 20 candidate targets of rhizome coptidis and turmeric under the HalfTarget
From: Heterogeneous network propagation for herb target identification
Rhizoma coptidis | Turmeric | ||||
|---|---|---|---|---|---|
Rank | Candidate Target | Score | Rank | Candidate Target | Score |
1 | PTGS2 | 0.0311 | 1 | CASP3 | 0.0657 |
2 | NOS2 | 0.0285 | 2 | TNF | 0.0619 |
3 | BAX | 0.0259 | 3 | BCL2 | 0.0518 |
4 | CASP9 | 0.0252 | 4 | JUN | 0.0438 |
5 | CDKN1A | 0.0238 | 5 | VEGFA | 0.0424 |
6 | NFKBIA | 0.0220 | 6 | BAX | 0.0400 |
7 | FOS | 0.0212 | 7 | IL6 | 0.0390 |
8 | CDK2 | 0.0203 | 8 | MMP9 | 0.0355 |
9 | VEGFA | 0.0202 | 9 | CASP9 | 0.0334 |
10 | IL4 | 0.0178 | 10 | AKT1 | 0.0326 |
11 | BCL2L1 | 0.0160 | 11 | CCND1 | 0.0302 |
12 | AKT1 | 0.0146 | 12 | CDK2 | 0.0296 |
13 | HERC5 | 0.0143 | 13 | MAPK1 | 0.0282 |
14 | CDC2 | 0.0135 | 14 | CDK4 | 0.0269 |
15 | EIF6 | 0.0132 | 15 | XDH | 0.0245 |
16 | MMP9 | 0.0130 | 16 | SOD1 | 0.0241 |
17 | IL2 | 0.0126 | 17 | PRKCB | 0.0233 |
18 | MPO | 0.0121 | 18 | CYP3A4 | 0.0213 |
19 | EGFR | 0.0120 | 19 | VCAM1 | 0.0211 |
20 | HIF1A | 0.0118 | 20 | MYC | 0.0202 |