Table 4 The top 20 candidate targets of rhizome coptidis and turmeric under the NoTarget
From: Heterogeneous network propagation for herb target identification
Rhizoma coptidis | Turmeric | ||||
|---|---|---|---|---|---|
Rank | Candidate Target | Score | Rank | Candidate Target | Score |
1 | CASP3 | 0.4526 | 1 | CASP3 | 0.2750 |
2 | RELA | 0.4109 | 2 | RELA | 0.2554 |
3 | PTGS2 | 0.3834 | 3 | PTGS2 | 0.2222 |
4 | TNF | 0.2988 | 4 | TNF | 0.1816 |
5 | NOS2 | 0.2771 | 5 | BCL2 | 0.1716 |
6 | BCL2 | 0.2708 | 6 | NOS2 | 0.1624 |
7 | CYP3A4 | 0.2325 | 7 | BAX | 0.1403 |
8 | SOD1 | 0.2132 | 8 | TP53 | 0.1349 |
9 | BAX | 0.2096 | 9 | JUN | 0.1318 |
10 | CASP9 | 0.1928 | 10 | CYP3A4 | 0.1230 |
11 | IL6 | 0.1846 | 11 | SOD1 | 0.1182 |
12 | JUN | 0.1777 | 12 | FOS | 0.1165 |
13 | CDKN1A | 0.1701 | 13 | CASP9 | 0.1158 |
14 | TP53 | 0.1701 | 14 | VEGFA | 0.1141 |
15 | IL1B | 0.1658 | 15 | IL6 | 0.1111 |
16 | VEGFA | 0.1612 | 16 | CDKN1A | 0.1106 |
17 | FOS | 0.1561 | 17 | NFKBIA | 0.0992 |
18 | ICAM1 | 0.1558 | 18 | IL1B | 0.0926 |
19 | HMOX1 | 0.1502 | 19 | MMP9 | 0.0873 |
20 | MAPK1 | 0.1358 | 20 | ICAM1 | 0.0872 |