Table 2 Subject demographic characteristics and severity classifications: validation data
From: Using medication utilization information to develop an asthma severity classification model
Variables | All asthma, (n = 3628) | Classified by Asthma severity, n (%) | p-value | |||
|---|---|---|---|---|---|---|
Stage 1 (n = 2276, 62.73%) | Stage 2 (n = 230, 6.34%) | Stage 3 (n = 807, 22.24%) | Stage 4 (n = 315, 8.68%) | |||
Gender, n (%) | 0.7073 | |||||
Female | 2107 (58.08) | 1309 (57.51) | 141 (61.30) | 472 (58.49) | 185 (58.73) | |
Male | 1521 (41.92) | 967 (42.49) | 89 (38.70) | 335 (41.51) | 130 (41.27) | |
Age, n (%) | <.0001 | |||||
18–34 | 874 (24.09) | 503 (22.10) | 72 (31.30) | 221 (27.39) | 78 (24.76) | |
35–44 | 586 (16.15) | 346 (15.20) | 40 (17.39) | 145 (17.97) | 55 (17.46) | |
45–54 | 686 (18.91) | 430 (18.89) | 48 (20.87) | 150 (18.59) | 58 (18.41) | |
55–64 | 588 (16.21) | 371 (16.30) | 41 (17.83) | 123 (15.24) | 53 (16.83) | |
≧65 | 894 (24.64) | 626 (27.50) | 29 (12.61) | 168 (20.82) | 71 (22.54) | |
CCI, Mean (SD) | 0.41 (0.86) | 0.44 (0.88) | 0.30 (0.69) | 0.38 (0.86) | 0.35 (0.76) | 0.0252 |
Obesity, n (%) | 18 (0.50) | 12 (0.53) | 0 (0.00) | 4 (0.50) | 2 (0.63) | 0.8377 |
Sinusitis, n (%) | 35 (0.96) | 21 (0.92) | 4(1.74) | 7(0.87) | 3(0.95) | 0.5970 |
GERD, n (%) | 10 (0.28) | 6 (0.26) | 0 (0.00) | 4 (0.50) | 0 (0.00) | 0.5579 |
Medication utilization, n (%) | ||||||
ICS/LABA | 853 (23.51) | 0 (0.00) | 0 (0.00) | 658 (81.54) | 195 (61.90) | <.0001 |
ICS | 331 (9.12) | 0 (0.00) | 227 (98.70) | 90 (11.15) | 14 (4.44) | <.0001 |
OCS | 358 (9.87) | 0 (0.00) | 0 (0.00) | 188 (23.30) | 170 (53.97) | <.0001 |
SABA | 870 (23.98) | 428 (18.80) | 82 (35.65) | 299 (37.05) | 61 (19.37) | <.0001 |
SAMA | 133 (3.67) | 66 (2.90) | 9 (3.91) | 46 (5.70) | 12 (3.81) | 0.0040 |
SABA/SAMA | 119 (3.28) | 51 (2.24) | 9 (3.91) | 46 (5.70) | 13 (4.13) | <.0001 |
# of patient having acute exacerbation, n (%) | 361 (9.95) | 186 (8.17) | 21 (9.13) | 118 (14.62) | 36 (11.43) | <.0001 |
Hospitalization | 59 (1.63) | 26 (1.14) | 1 (0.43) | 21 (2.60) | 11 (3.49) | 0.0007 |
Emergency department visit | 174 (4.80) | 83 (3.65) | 11 (4.78) | 66 (8.18) | 14 (4.44) | <.0001 |
Short-acting drug | 230 (6.34) | 121 (5.32) | 11 (4.78) | 74 (9.17) | 24 (7.62) | 0.0008 |