Association Between Borderline Hyponatremia and Mortality |
 | OR (IC95%) | P | AIC |
Classical Modela
| 1.98 (1.73–2.68) | <.001 | 8098.4 |
PheWAS Modelb
| 2.59 (2.28–2.94) | <.001 | 11,002 |
Final Modelc
| 1.57 (1.35–1.81) | <.001 | 7585.5 |
Association Between Borderline Hypernatremia and Mortality |
 | OR (IC95%) | P | AIC |
Classical Modeld
| 3.72(1.53–8.45) | <.001 | 6077.9 |
PheWAS Modele
| 6.23(4.60–8.33) | <.001 | 8761.9 |
Final Modelf
| 3.47(2.43–4.90) | <.001 | 5920.8 |
- Confounding Factors Retained in the different models:
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aClassical model: age, duration of hospital stay, number of ICD-10 codes, hospital admissions via the emergency department, ICU stay, dialysis, palliative care, Charlson Comorbidity Index
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bPheWAS model: A41, I20, I25, I48, I71, J15, J80, J96, K65, R07, R57, Z48, Z51
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cFinal model: classical model + I20, I25, I48, J80, R57, Z48, Z51
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dClassical model: age, duration of hospital stay, number of ICD-10 codes, hospital admissions via the emergency department, ICU stay, dialysis, palliative care, Charlson Comorbidity Index
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ePheWAS model: J69, J80, J96, N17, R57, S06
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fFinal model: classical model + J69, J80, R57, S06