Association Between Borderline Hyponatremia and Mortality
|
|
OR (IC95%)
|
P
|
AIC
|
Classical Modela
|
1.98 (1.73–2.68)
|
<.001
|
8098.4
|
PheWAS Modelb
|
2.59 (2.28–2.94)
|
<.001
|
11,002
|
Final Modelc
|
1.57 (1.35–1.81)
|
<.001
|
7585.5
|
Association Between Borderline Hypernatremia and Mortality
|
|
OR (IC95%)
|
P
|
AIC
|
Classical Modeld
|
3.72(1.53–8.45)
|
<.001
|
6077.9
|
PheWAS Modele
|
6.23(4.60–8.33)
|
<.001
|
8761.9
|
Final Modelf
|
3.47(2.43–4.90)
|
<.001
|
5920.8
|
- Confounding Factors Retained in the different models:
-
aClassical model: age, duration of hospital stay, number of ICD-10 codes, hospital admissions via the emergency department, ICU stay, dialysis, palliative care, Charlson Comorbidity Index
-
bPheWAS model: A41, I20, I25, I48, I71, J15, J80, J96, K65, R07, R57, Z48, Z51
-
cFinal model: classical model + I20, I25, I48, J80, R57, Z48, Z51
-
dClassical model: age, duration of hospital stay, number of ICD-10 codes, hospital admissions via the emergency department, ICU stay, dialysis, palliative care, Charlson Comorbidity Index
-
ePheWAS model: J69, J80, J96, N17, R57, S06
-
fFinal model: classical model + J69, J80, R57, S06