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Table 4 Comparison with prevalence in the literature

From: A novel data-driven workflow combining literature and electronic health records to estimate comorbidities burden for a specific disease: a case study on autoimmune comorbidities in patients with celiac disease

  This study Cosnes et al. [33] Iqbal et al. [2] Volta et al. [5] Collin et al. [22] Størdal et al. [6] Diamanti et al. [1] Van der Pals et al. [13] Sategna-Guidetti et al. [27] Counsell et al. [34]
Study characteristics
 Population 741 adults 378 children, 546 adults 356 adults (> 12 yo) 770 adults 335 adults 3006 children 558 children 335 children 241 adults (untreated) 107 adults
 Information source EHR question-naire question-naire question-naire hospital records national register serology serology serology serology
 Origin France France Canada Italy Finland Norway Italy Sweden Italy Scotland
 Year 2015 2008 2013 2012 1994 2011 2011 2014 2001 1994
Prevalence, % (95% CI)
 Autoimmune thyroiditis 12.6 (10.1, 14.9) 6.0 10.6 26.3 7.5 1.4 12.0 7.7 30.2 15.0
 Type 1 diabetes mellitus 2.3 (1.2, 3.4) 6.5 2.2 3 5.4 4.7     
 Dermatitis herpetiformis 2.0 (1.0, 3.0) 3.1 13.5 4       
 Rheumatoid disease 0.9 (0.3, 1.6) 0.7 4.5   1.8      
 Autoimmune hepatitis 0.9 (0.3, 1.6) 1.2 0.0        
 Sjögren’s syndrome 0.8 (0.2, 1.5) 0.2 0.8   3.3      
 Addison’s disease 0.4 (0.1, 1.2) 0.2    0.6      
 Systemic lupus 0.3 (0.1, 1.0) a 0.2 1.1        
 Multiple sclerosis 0.1 (0.0, 0.8) a 0.1         
 Antiphospholipid syndrome 0 (0.0, 0.5) a 0.2         
 Myasthenia gravis 0 (0.0, 0.5) a 0.2         
  1. CI95: 95% confidence interval, a Wilson’s interval