Table 3 Support of the selected tools with respect to themes and their features

Team and contribution management

collaboration

Web-based application

Web-based application

-

Web-based application

Web-based application

Access

• Sign-up as a new user

• Sign in with Google+

Sign-up as a new user

-

By invitation to email address

By invitation to email address

Role

• Viewer

• Reviewer

• Author

• Admin

• Admin

• Researcher

• No access

• Panel member

-

-

• Coordinator

• Leader

• Members

• Patient

• Expert

Conflict of interest

-

Based on:

• ICMJE [48]

• WHO [47]

• NHF

• MSPSC [18]

-

-

Their own COI form

Project management

Development checklist

• Planning

• Content development

• Publication, evaluation and updating

-

-

-

-

Milestones and deadlines

• Task title

• Date

• Owner

• Comment

• Task title

• Due date

-

-

• Title

• Date

• Time

• Place

• Contact person

Progress monitoring

Manual

• Evidence profiles

• Guidelines

-

-

-

• Voting status

• survey status

• Activity log

Evidence management

Search strategy and history

Redirect search query to 6 external search engines:

-Epistemonikos [69]

-SuperFilters

-PubMed

-International Guideline Library

-Dynamed

-The Knowledge Egg

-

-

-

Document search strategy along with the import history in a literature collection.

Evidence repository

As an attached file to an imported reference

-

-

-

• Bibliographic data

• Abstract

• Attach files (PDF)

Citations

From reference library (imported references)

By adding hyperlink

-

By adding hyperlink

Link the citation manually

Reference manager

To some extent

-

-

-

-

Guideline development

Evidence assessment

GRADE

GRADE

-

-

• Sign [53]

• Oxford [54]

Quality rating

GRADE

GRADE

• GRADE

• AAP

• APTA

• ASPEN

• ACEP

• ASCO

• AUA

-

-

Controlled natural language

-

-

For authoring recommendation.

-

-

Deontic terminology

-

-

Automatically is suggested by the tool based on equilibrium or the preponderance of benefits, risks, harms and costs, and evidence quality.

-

-

Voting

By the integration with iEtD from all PICOs.

Only in the process of formulating guideline questions

-

-

Can be customized for different purposes

Document management

Change control (tracking)

Not for the full guideline. Only on text

-

-

-

Not for the full guideline. Only on: Text, comments, Files

Managing versions (version control)

-

-

-

-

For content type “text”

Template-based authoring

Template for some sections of a guideline.

Flexible template in the embedded text editor including subject-headings

For developing recommendations.

-

-

Guideline repository management

Online database

Online database

No Database. The file should be stored by users manually on their own PC.

Online database

Online database

Guideline content enhancement

Tagging

• ICD-10

• SNOMED-CT

• ATC

• RxNorm

• MeSH

• ICPC-2

• LOINC

• UMLS

• NEKLAB (Norwegian lab coding)

-

-

• MeSH

-

EHR linking

• Open EHR [70]

-

-

-

-

Import, export and publication

Import file formats

References:

• Manually

• Import from PubMed,

• Import RIS file

SoF:

• RevMan5

-

Attach to guidelines:

• PDF file

Bibliographic data including abstract:

• XML

SoF:

• RevMan5 (import as a reference)

• MS Word

• PDF

Export file formats

Guideline:

• PDF

• JSON

Recommendation:

• MS Word

• PDF

• HTML

Recommendation

• MS Word

Guideline:

• PDF

Bibliographic:

• Medline and EndNote generated XML

Evidence profile and PICO:

• JSON

• RevMan5

• MS Word

• MAGIC file format

SoF:

• RevMan5

• PDF

• MS Word

• HTML

Publishing

Web and specific apps for phone and tablets with offline access

• Web

• Mobile

-

• Web

• Web

User experience enhancement

Wizard-based authoring

-

Only for

• COIs management

• Voting process

Only for

• Developing recommendation

-

-

Walkthrough user guide

-

For the main implemented features

-

-

-

User manual

• Yes

• Yes

• Yes

-

• Yes