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Table 1 Predictors for all cases, by each class, and univariate class comparisons

From: Predicting two-year survival versus non-survival after first myocardial infarction using machine learning and Swedish national register data

Predictors (n = 39)

All cases (n = 51,943)

Survivors (n = 46,233)

Non-survivors (n = 5710)

Survivors vs. Non-survivors (P)

Age (yrs)

68.8 ± 12.3

67.5 ± 11.9

79.3 ± 9.8

< 0.0001

Male sex

33,620 (64.7)

30,523 (66.0)

3097 (54.2)

< 0.0001

Weight (kg)

79.1 ± 15.9

72.1 ± 15.6

80.0 ± 16.3

< 0.0001

Ambulance to CCU

31,654 (60.9)

27,816 (60.2)

3838 (67.2)

< 0.0001

Comorbid conditions

 Smoking

12,717 (24.5)

11,740 (25.4)

977 (17.1)

< 0.0001

 Diabetes

8552 (16.5)

7046 (15.2)

1506 (26.4)

< 0.0001

 Hypertension

23,432 (45.1)

20,386 (44.1)

3046 (53.3)

< 0.0001

 Previous stroke

3623 (7.0)

2759 (6.0)

864 (15.1)

< 0.0001

Admission medication

 ACE inhibitors

8409 (16.2)

7096 (15.3)

1313 (23.0)

< 0.0001

 A2 blockers

5893 (11.3)

5164 (11.2)

729 (12.8)

0.0003

 Beta blockers

14,485 (27.9)

12,084 (26.1)

2401 (42.0)

< 0.0001

 Statins

9904 (19.1)

8677 (18.8)

1227 (21.5)

< 0.0001

Presenting symptoms

 Chest pain

44,589 (85.8)

40,761 (88.2)

3828 (67.0)

< 0.0001

 Dyspnea

3472 (6.7)

2368 (5.1)

1104 (19.3)

< 0.0001

 Other

3580 (6.9)

2834 (6.1)

746 (13.1)

< 0.0001

ECG rhythm at CCU

 Sinus

46,297 (89.1)

41,983 (90.8)

4314 (75.6)

< 0.0001

 Atrial fibrillation

4469 (8.6)

3308 (7.2)

1161 (20.3)

< 0.0001

ECG QRS at CCU

 Normal

35,819 (69.0)

32,709 (70.7)

3110 (54.5)

< 0.0001

 Pathological Q-wave

5407 (10.4)

4753 (10.3)

654 (11.5)

0.0062

 Left bundle branch block

2458 (4.7)

1877 (4.1)

581 (10.2)

< 0.0001

 Other

5711 (11.0)

4862 (10.5)

849 (14.9)

< 0.0001

ECG STT at CCU

 Normal

11,729 (22.6)

10,805 (23.4)

924 (16.2)

< 0.0001

 ST-elevation

17,641 (34.0)

16,251 (35.2)

1390 (24.3)

< 0.0001

 ST-depression

11,462 (22.1)

9690 (21.0)

1772 (31.0)

< 0.0001

 Other

5820 (11.2)

4726 (10.2)

1094 (19.2)

< 0.0001

Pulmonary rales at CCU

 No

46,205 (89.0)

42,081 (91.0)

4124 (72.2)

< 0.0001

 Rales

3880 (7.5)

2762 (6.0)

1118 (19.6)

< 0.0001

Other measures at CCU

 Troponin (ng)

1360 (310–6460)

1350 (280–1587)

1400 (319–10,000)

0.1761

 HR(bpm)

76 (65–90)

75 (65–90)

86 (71–86)

< 0.0001

 SBP (mm Hg)

148.9 ± 28.6

143.0 ± 28.2

150.0 ± 30.7

< 0.0001

Reperfusion at CCU

 No

34,469 (66.4)

29,740 (64.3)

4729 (82.8)

< 0.0001

 Primary PCI

14,665 (28.2)

13,884 (30.0)

781 (13.7)

< 0.0001

Discharge medication

 ACE inhibitors

31,547 (60.7)

28,712 (62.1)

2835 (49.6)

< 0.0001

 A2 blockers

6445 (12.4)

5670 (12.3)

775 (13.6)

0.0046

 Oral anticoagulants

2993 (5.8)

2514 (5.4)

479 (8.4)

< 0.0001

 Other antiplatelet

41,741 (80.4)

38,461 (83.2)

3280 (57.4)

< 0.0001

 Beta blockers

46,623 (89.8)

41,789 (90.4)

4834 (84.7)

< 0.0001

 Statins

45,366 (87.3)

41,918 (90.7)

3448 (60.4)

< 0.0001

ECG rhythm at discharge

 Atrial fibrillation

3703 (7.1)

2645 (5.7)

1058 (18.5)

< 0.0001

  1. Values are mean ± SD or median (IQR) or count (%). Uncorrected P-values are from Welch’s t-tests if variable is Gaussian, Mann-Whitney U-tests if non-Gaussian, or Pearson’s χ2-tests if categorical
  2. ACE angiotensin-converting-enzyme, A2 angiotensin-2 receptor, CCU coronary care unit, ECG electrocardiogram, HR heart rate, PCI percutaneous coronary intervention, SBP systolic blood pressure