Skip to main content

Advertisement

Table 4 Comparison of CMOST with other microsimulation tools. Screening colonoscopies were performed at 10-year intervals between ages 50 and 75 years. Results of the microsimulation tools MISCAN, CRC-SPIN, and SimCRC were taken from reference [7]. Numbers indicate percentage reduction or the number of additional colonoscopies or CRC cases as indicated per 1000 individuals. For CMOST, the numbers of the baseline scenario assuming a dwell time of 13 years (CMOST13) are given; numbers in parenthesis indicate results obtained by using CMOST8 and CMOST19

From: CMOST: an open-source framework for the microsimulation of colorectal cancer screening strategies

  MISCAN CRC-SPIN SimCRC CMOST13 (CMOST8, CMOST19)
Incidence reduction 52% 91% 82% 53% (55, 48)
Mortality reduction 65% 92% 84% 61% (65, 55)
Life years gained 207 260 327 142 (155, 121)
Screening colonoscopies 2288 2580 2574 2373 (2304, 2289)
Surveillance colonoscopies 1715 1341 1609 1311 (1222, 1251)
Total colonoscopies 4002 3921 4184 3600 (3538, 3558)
CRC cases prevented 30 56 54 27 (28, 23)
CRC mortality cases prevented 19 25 30 12 (13, 10)
Colonoscopies per case prevented 135 70 77 132 (124, 155)
Colonoscopies per LYG 19 15 13 25 (22, 29)