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Table 2 Variant effects of FANCC on entorhinal cortex thickness. P-values from SKAT were obtained by removing a rare variant on FANCC at a time

From: Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s disease

Variant

p-valuea

Annotation

rs1800361

3.01E-04

nonsynonymous

rs145497019

1.20E-05

nonsynonymous

rs1800362

9.71E-06

nonsynonymous

rs1800368

9.71E-06

nonsynonymous

rs138629441

5.79E-06

nonsynonymous

rs143152201

3.19E-06

nonsynonymous

9:97869388

2.33E-06

nonsynonymous

FANCC

2.27E-06b

 

9:97887391

2.27E-06

nonsynonymous

rs1800367

2.27E-06

nonsynonymous

9:97876956

2.20E-06

nonsynonymous

rs140687953

1.87E-06

nonsynonymous

rs140781259

1.70E-06

nonsynonymous

9:97934335

1.66E-06

nonsynonymous

rs1800366

1.65E-06

nonsynonymous

rs121917783

1.59E-06

stop-gain

rs1800365

1.48E-06

nonsynonymous

  1. a p-value from SKAT for FANCC after removing the variant
  2. b p-value from SKAT for FANCC that contains every variant
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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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