Skip to main content
Fig. 3 | BMC Medical Informatics and Decision Making

Fig. 3

From: Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s disease

Fig. 3

Functional networks based on top 5 genes associated with entorhinal cortex thickness. The Integrated Multi-species Prediction (IMP) performs a graphical search of a functional network to identify the genes most likely to participate in similar pathways as query genes including FANCC, RFX1, FAF1, ABCA5 and SORCS2. Nodes represent genes and edges represent the predicted probability that the connected genes are involved in the same biological process. Large nodes represent query genes and the color of the edge signifies the strength of the relationship confidence. Red edge represents higher confidence scores between nodes

Back to article page