Fig. 2From: Knowledge-driven binning approach for rare variant association analysis: application to neuroimaging biomarkers in Alzheimer’s diseaseManhattan plot of genome-wide gene-based rare variant association analysis for a LOAD-related neuroimaging endophenotype, entorhinal cortex thickness. –log10 p-value was plotted against the chromosomal location of each gene. FANCC exceeded the genome-wide significant threshold (FDR-corrected p-value = 0.05) (red line)Back to article page