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Table 1 39 AKU patients show CatD values included between 18,76–185,2 ng/mL (measured with ELISA in serum samples) with a mean and standard deviation 62,54 ± 41,45 ng/mL

From: ApreciseKUre: an approach of Precision Medicine in a Rare Disease

 

AKU patients

Reference values

CysC mg/L (ELISA)

 Samples

29 M 11 F

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 Min-max

M:0.60–1.00

F:0.40–0.90

M:0.71–1.02a

F:0.58–0.98a

 Mean ± SD

M:0.70 ± 0.15

F:0.71 ± 0.14

M:0.86 ± 0.15a

F:0.78 ± 0.20a

CatD ng/mL (ELISA)

 Samples

39

12

 Min-max

18.76–185.2

36.35–56.72

 Mean ± SD

62.54 ± 41.45

46.68 ± 5.88

HGA μM (ELISA)

 Samples

40

8

 Min-max

13.40–54.70

0.00

 Mean ± SD

25.89 ± 8.00

0.00

  1. The outliers 18.76 ng/mL; 19.24 ng/mL and 185.2 ng/mL are responsible for the high values of standard deviation. 12 healthy control show values included between 36,35 and 56,72 ng/mL (measured with ELISA in serum samples) with a mean and standard deviation of 46,68 ± 5,88 ng/mL. 29 AKU male patients show CysC values included between 0,60 mg/L and 1,00 mg/L (measured with ELISA in serum samples) with a mean and standard deviation 0,70 ± 0,15 mg/L, 11 AKU female patients show CysC values included between 0,40 mg/L and 0,90 mg/L (measured with ELISA in serum samples) with a mean and standard deviation 0,71 ± 0,14 mg/L. Reference values differ in many populations and with sex and age: for women, the average reference interval is 0.52 to 0.90 mg/L with a mean of 0.71 mg/L. For men, the average reference interval is 0.56 to 0.98 mg/L with a mean of 0.77 mg/L [11]. 40 AKU patients show HGA values included between 13,40 and 54,70 μM (measured with ELISA in serum samples) with a mean and standard deviation 25,89 ± 8,00 μM. Thanks to correlation matrix we have verified all the possible correlations between HGA and the other biomarkers, but owing to its great variability, all the Pearson’s index show no statistically significant values
  2. a[11]