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Table 2 Pre- versus during-SMS program differences in prescription coverage

From: Impact of a clinical program using weekly Short Message Service (SMS) on antiretroviral therapy adherence support in South Africa: a retrospective cohort study

 

Full Cohort,N = 2255

<100% Baseline Coverage Subset, N = 725

Recent ART Initiators Subset, N = 416

Covariate

Adjusted Odds Ratio (95% CI); P-value

Age (per year)

1.03 (1.01–1.04); P  < 0.001

1.02 (1.01–1.03); P  = 0.001

1.03 (1.01–1.06); P  = 0.016

Female gender

1.55 (1.26–1.90); P  < 0.001

1.32 (1.03–1.68); P  = 0.027

0.92 (0.54–1.56); P = 0.751

Prior ART duration (per 30 days)

–

–

–

Prescription length (per 30 days)

1.28 (1.27–1.29); P  < 0.001

1.17 (1.16–1.19); P  < 0.001

1.31 (1.28–1.34); P  < 0.001

First line regimen

2.70 (2.33–3.12); P <0.001

4.30 (3.62–5.11); P  < 0.001

5.52 (3.92–7.77); P  < 0.001

Fixed dose combination

2.71 (2.62–2.81); P  < 0.001

3.51 (3.33–3.70); P  < 0.001

2.88 (2.67–3.10); P  < 0.001

During-program period

0.61 (0.56–0.66); P  < 0.001

1.56 (1.42–1.71); P  < 0.001

0.53 (0.45–0.63); P  < 0.001

Pre-program period coverage (by Group):

Exposed vs. Unexposed

1.05 (0.79–1.39); P = 0.732

1.00 (0.72–1.39); P = 0.992

2.53 (1.11–5.77); P  = 0.028

Unknown vs. Unexposed

1.60 (1.02–2.51); P  = 0.040

1.48 (0.85–2.57); P = 0.166

3.07 (1.01–9.35); P  = 0.049

Program Effect (= During-program period coverage, by Group, adjusting for the variables above):

Exposed vs. Unexposed

1.23 (1.13–1.34); P  < 0.001

1.29 (1.17–1.43); P  < 0.001

1.17 (0.97–1.42); P = 0.101

Unknown vs. Unexposed

0.47 (0.41–0.54); P  < 0.001

0.67 (0.57–0.80); P  < 0.001

0.33 (0.24–0.45); P  < 0.001

  1. This table presents output from the mixed effects logistic regression on prescription coverage for a given day. The Groups are as follows: “Exposed” patients were sent the SMS; “Unexposed” patients did not have mobile phone numbers and thus were not sent SMS; “Unknown” patients had unknown phone number statuses due to missing charts, and thus also were not sent SMS. The “<100% Baseline Coverage Subset” includes patients with coverage < 100% in the pre-program period. The “Recent ART Initiators Subset” includes patients who initiated ART within 2 years of the SMS program start. The backward stepwise selection process of model parameters led to the omission of prior ART duration. CI = confidence interval. Bold indicates statistical significance at P < =0.05
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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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