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Fig. 1 | BMC Medical Informatics and Decision Making

Fig. 1

From: Prognostic factor analysis for breast cancer using gene expression profiles

Fig. 1

Overall workflow The expression profiles of 24,924 genes were used for the survival log-rank test. Two gene groups were chosen as highly expressed genes (H1, H2), and low-expressed genes (L1, L2) associated with poor survival were clustered according to positive correlations. Negative correlations were used for pairing across differentially expressed gene sets. Finally, four paired gene sets were selected. To estimate the prognostic scores, the ratio of the level of high- and low-expressed genes was defined as the score

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