Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data

John, Ann; McGregor, Joanne; Fone, David; Dunstan, Frank; Cornish, Rosie; Lyons, Ronan A.; Lloyd, Keith R.

doi:10.1186/s12911-016-0274-7

BMC Medical Informatics and Decision Making

Table 2 Sensitivity, specificity, positive predictive value-results comparing GP Read codes for anxiety and depression diagnoses, symptoms and treatment with MHI-5 data (as the gold standard) from the CHSNS waves

From: Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data

Algorithm: CMD diagnosis/symptom/treatment	Wave (W)	True Positives^a	True negatives^b	Sensitivity	Specificity	Positive Predictive value	Number of cases identified by algorithm n (prevalence, %)–includes false positives W1, n = 2584 W2, n = 1195
1. Current treatment only	W1	268	1590	0.33	0.90	0.61	438 (17.0)
1. Current treatment only	W2	189	712	0.48	0.89	0.68	277 (23.2)
2. Current diagnosis (treated or untreated)	W1	50	1737	0.06	0.99	0.68	73 (2.8)
2. Current diagnosis (treated or untreated)	W2	20	792	0.05	0.99	0.71	28 (2.3)
3. Current diagnosis treated	W1	48	1742	0.06	0.99	0.73	66 (2.6)
3. Current diagnosis treated	W2	18	793	0.05	0.99	0.72	25 (2.1)
4. Current diagnosis or symptom (treated or untreated)	W1	57	1733	0.07	0.99	0.68	84 (3.3)
4. Current diagnosis or symptom (treated or untreated)	W2	37	783	0.09	0.98	0.69	54 (4.5)
5. Current diagnosis or symptom (treated only)	W1	53	1738	0.06	0.99	0.71	75 (2.9)
5. Current diagnosis or symptom (treated only)	W2	32	785	0.08	0.98	0.68	47 (3.9)
6. Current treatment plus untreated current diagnosis or symptom	W1	272	1585	0.33	0.90	0.61	447 (17.3)
	W2	194	710	0.49	0.89	0.68	284 (23.8)
7. Historical or current diagnosis currently treated	W1	121	1697	0.15	0.96	0.66	184 (7.1)
7. Historical or current diagnosis currently treated	W2	113	765	0.29	0.96	0.76	148 (12.4)
8. Historical or current diagnosis or symptom currently treated	W1	131	1693	0.16	0.96	0.67	198 (7.7)
	W2	138	750	0.35	0.94	0.73	188 (15.7)
9. Historical diagnosis currently treated plus current diagnosis (treated or untreated)	W1	123	1692	0.15	0.96	0.64	191 (7.4)
	W2	115	764	0.29	0.96	0.76	151 (12.6)
10. Historical diagnosis currently treated plus current diagnosis or symptom (treated or untreated)	W1	127	1691	0.16	0.96	0.65	196 (7.6)
	W2	126	756	0.32	0.95	0.74	170 (14.2)
11. Historical or current diagnosis or symptom currently treated plus current diagnosis untreated	W1	133	1688	0.16	0.96	0.65	205 (7.9)
	W2	140	749	0.35	0.94	0.73	191 (16.0)
12. Historical or current diagnosis or symptom currently treated plus current diagnosis or symptom untreated	W1	135	1688	0.17	0.96	0.65	207 (8.0)
	W2	143	748	0.36	0.94	0.73	195 (16.3)

^aNumber identified with CMD using MHI-5 data at Wave 1 = 824, at Wave 2 = 395
^bNumber identified as not having CMD at Wave 1 = 1760, at Wave 2 = 800

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ISSN: 1472-6947

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