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Table 2 Sensitivity, specificity, positive predictive value-results comparing GP Read codes for anxiety and depression diagnoses, symptoms and treatment with MHI-5 data (as the gold standard) from the CHSNS waves

From: Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data

Algorithm: CMD diagnosis/symptom/treatment Wave (W) True Positivesa True negativesb Sensitivity Specificity Positive Predictive value Number of cases identified by algorithm n (prevalence, %)–includes false positives W1, n = 2584 W2, n = 1195
1. Current treatment only W1 268 1590 0.33 0.90 0.61 438 (17.0)
W2 189 712 0.48 0.89 0.68 277 (23.2)
2. Current diagnosis (treated or untreated) W1 50 1737 0.06 0.99 0.68 73 (2.8)
W2 20 792 0.05 0.99 0.71 28 (2.3)
3. Current diagnosis treated W1 48 1742 0.06 0.99 0.73 66 (2.6)
W2 18 793 0.05 0.99 0.72 25 (2.1)
4. Current diagnosis or symptom (treated or untreated) W1 57 1733 0.07 0.99 0.68 84 (3.3)
W2 37 783 0.09 0.98 0.69 54 (4.5)
5. Current diagnosis or symptom (treated only) W1 53 1738 0.06 0.99 0.71 75 (2.9)
W2 32 785 0.08 0.98 0.68 47 (3.9)
6. Current treatment plus untreated current diagnosis or symptom W1 272 1585 0.33 0.90 0.61 447 (17.3)
W2 194 710 0.49 0.89 0.68 284 (23.8)
7. Historical or current diagnosis currently treated W1 121 1697 0.15 0.96 0.66 184 (7.1)
W2 113 765 0.29 0.96 0.76 148 (12.4)
8. Historical or current diagnosis or symptom currently treated W1 131 1693 0.16 0.96 0.67 198 (7.7)
W2 138 750 0.35 0.94 0.73 188 (15.7)
9. Historical diagnosis currently treated plus current diagnosis (treated or untreated) W1 123 1692 0.15 0.96 0.64 191 (7.4)
W2 115 764 0.29 0.96 0.76 151 (12.6)
10. Historical diagnosis currently treated plus current diagnosis or symptom (treated or untreated) W1 127 1691 0.16 0.96 0.65 196 (7.6)
W2 126 756 0.32 0.95 0.74 170 (14.2)
11. Historical or current diagnosis or symptom currently treated plus current diagnosis untreated W1 133 1688 0.16 0.96 0.65 205 (7.9)
W2 140 749 0.35 0.94 0.73 191 (16.0)
12. Historical or current diagnosis or symptom currently treated plus current diagnosis or symptom untreated W1 135 1688 0.17 0.96 0.65 207 (8.0)
W2 143 748 0.36 0.94 0.73 195 (16.3)
  1. aNumber identified with CMD using MHI-5 data at Wave 1 = 824, at Wave 2 = 395
  2. bNumber identified as not having CMD at Wave 1 = 1760, at Wave 2 = 800