Figure 2

The workflow charts of the BioSunMS. To construct model for patients classification using peptide profiles generated by MALDI-TOF MS or SELDI-TOF MS, following steps are suggested. The first step is to input patients information, then preprocessing of MS spectra data for each patient, linking MS peaks to each patient through sample ID, peak alignment and creation of data matrix, t-test based feature selection and SVM-based model construction. Finally, the ROC curve was used to evaluate the performance of the model.