The first-year growth response to growth hormone treatment predicts the long-term prepubertal growth response in children

Table 2 The characteristics of the children included in the test groups of children born prematurely (n = 19) and in children from other continents (n = 78).

	Preterm (6 girls, 13 boys)				From foreign continents (27 girls, 51 boys)
Variables	Median	Min	Max	n	Median	Min	Max	n
At birth
Gestational age (weeks)	35	32	36	19	38.5	27	41	28
Height at birth SDS	-2.55	-8.09	1.43	19	-1.76	-3.91	0.38	6
Weight at birth SDS	-2.25	-6.12	0.11	19	-1.27	-3.95	0.63	8
At GH start
Age at start of GH treatment (yrs)	6.38	3.02	10.1	19	8.35	3.13	13.47	78
Height SDS	-2.81	-4.08	-2.01	19	-3.27	-6.31	-0.74	78
Weight SDS	-2.78	-5.15	-1.56	19	-3.11	-5.66	1.12	78
Weight for height SDS	-0.97	-3.29	0.71	19	-0.71	-3.8	4.23	78
BMI (kg/m²)	14.5	12.18	16.5	19	15.35	11.49	22.23	78
Change in height SDS during pre-treatment year	0	-0.45	0.52	17	0.07	-0.73	0.59	69
Target height SDS	-0.58	-1.89	1.26	19	-1.23	-3.72	0.5	39
Father height SDS	-1.13	-3.41	1.3	19	-2.04	-4.62	0.54	39
Mother height SDS	-0.84	-3.39	1.55	19	-2.07	-5.85	0.4	41
Diff MPH SDS	-2.23	-3.43	-1.27	19	-1.76	-4.35	1.27	39
GH_max during AITT (mU/L)	24.15	11	70.4	18	20.72	1.09	135.57	30
GH_max of 24 h profile (mU/L)	19.95	14.3	48.05	11	42.69	12.37	88.79	43
IGF-I at GH-start	60	19	187	18	78	12	259	19
IGF-I SDS	-1.57	-5.42	0.72	18	-1.35	-7.02	1.75	19
GH dose (ug/kg.day)	0.037	0.027	0.043	19	0.033	0.023	0.047	78
During treatment
Change in height SDS first yr	0.67	0.47	1.16	19	0.68	-0.1	1.74	78
Change in height SDS during 2 yrs	0.92	0.63	1.69	19	1.06	0.11	2.79	78

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