Figure 3From: Integration of modeling and simulation into hospital-based decision support systems guiding pediatric pharmacotherapyDiagnostic plots from preliminary methotrexate population pharmacokinetic model. (A) Observed versus population predicted concentrations. (B) Observed versus individual predicted concentrations. Open circles represent MTX plasma concentrations from patients predicted to have normal renal function. Open triangles represent patients predicted to have reduced MTX clearance.Back to article page