Extensions to decision curve analysis, a novel method for evaluating diagnostic tests, prediction models and molecular markers

Table 1 Comparison of decision curve analysis with traditional statistical and decision-analytic methods

	Traditional statistical analysis	Traditional decision analysis	Decision curve analysis
Mathematics	Simple	Can be complex	Simple
Additional data	Not required	Patient preferences, treatment costs or effectiveness	General clinical estimates only
Predictors	Binary or continuous	Continuous predictors problematic	Binary or continuous
Assess clinical value?	No	Yes	Yes

ISSN: 1472-6947