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Table 2 Single Term with the Best Sensitivity (keeping Specificity ≥50%), Best Specificity (keeping Sensitivity ≥50%), and Best Optimization of Sensitivity and Specificity (based on the lowest possible absolute difference between sensitivity and specificity) for Detecting Studies of Causation in EMBASE in 2000

From: Developing optimal search strategies for detecting clinically sound and relevant causation studies in EMBASE

Search term OVID search* Sensitivity (%) (n = 215) Specificity (%) (n = 27,554) Precision (%)† Accuracy (%) (n = 27,769)
Best sensitivity
exp general aspects of disease
72.6 (66.6 to 78.5) 55.7 (55.1 to 56.3) 1.3 (1.1 to 1.5) 55.8 (55.2 to 56.4)
Best specificity
exp risk
50.7 (44.0 to 57.4) 87.5 (87.1 to 87.8) 3.1 (2.5 to 3.6) 87.2 (86.8 to 87.6)
Best Optimization of Sensitivity & Specificity
control:.mp.
60.9 (54.5 to 67.5) 66.4 (65.9 to 67.0) 1.4 (1.2 to 1.6) 66.4 (65.8 to 66.9)
  1. *The search strategy is reported using Ovid's search engine syntax for EMBASE.
  2. †Denominator varies by row.
  3. exp = explode, a search term that automatically includes closely related indexing terms; : = truncation; mp = multiple posting – term appears in title, abstract, or subject heading.