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Table 3 Average (st. dev.) 1 - c-index performance results of cox proportional hazards and random survival forest models as estimated by collating out-of-bag distributions from 100 bootstrap runs

From: Can multiple SNP testing in BRCA2 and BRCA1 female carriers be used to improve risk prediction models in conjunction with clinical assessment?

Model Average (st.dev.) 1 - c-index
  BRCA1 BRCA2
(i) GPS 0.468 (0.037)* 0.417 (0.021)*
(ii) GPS + Clin./Demogr. 0.221 (0.019) 0.215 (0.018)
(iii) SNPs 0.504 (0.026)* 0.469 (0.028)*
(iv) SNPs + Clin./Demogr. 0.238 (0.019) 0.241 (0.019)
(v) Clin./Demogr. 0.222 (0.019) 0.217 (0.018)
(vi) all variables (by AIC) 0.236 (0.018) 0.232 (0.019)
Random survival forest (all variables) 0.243 (0.019) 0.230 (0.019)
  1. *p > 0.0001 as compared to model (ii) by an adjusted t-test. Values in bold show the best performance.