Figure 2

Examples of VCM icons created by combining shapes, pictograms and colors. The simple “renal disorder” icon is created by assembling the red color (current state), the square (disease) and the kidney pictogram. It can then be further modified to create the “drug for renal disorder” icon (by adding a green cross top-right pictogram (meaning drug treatment)), or the “renal failure” icon (by adding a shape modifier showing a downward arrow (meaning a decrease or failure)).