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Table 4 Estimated probabilities (%) of morbidity and mortality from untreated SNPTB and side effects in treated SNPTB (median and inter quartile range)

From: Intuitive weights of harm for therapeutic decision making in smear-negative pulmonary Tuberculosis: an interview study of physicians in India, Pakistan and Bangladesh

  

India (n = 77)

Pakistan (n = 84)

Bangladesh (n = 81)

All countries (n = 242)

1

Mortality from untreated SNPTB*

70 (65-75)

60 (30-82.5)

60 (40-70)

65 (50-75)

2

Morbidity from untreated SNPTB¶

5 (5-10)

20 (10-30)

29.5 (20-30)

20 (8-30)

3

Probability of side effects occurring if SNPTB is treated¶

6 (3-9)

10 (5-20)

15 (10-29)

10 (5-20)

4

Conditional probability of death due to side effects if they occur when SNPTB is treated¶

5 (3-5)

10 (4.5-20)

12.5 (5-25)

8 (5-20)

5

Conditional probability of morbidity as a result of side effects when SNPTB is treated¶

10 (7-15)

25 (10-50)

15 (10-30)

15 (10-30)

6

Absolute probability of mortality arising from side effects of anti-TB treatment¶×

0.25 (0.11-0.45)

1.5 (0.71-10)

1(0.22-4.0)

0.70 (0.23-3.1)

7

Absolute probability of morbidity arising from side effect of anti-TB treatment¶π

0.6 (0.3-1)

3.0 (1-7.4)

3 (0.57-8)

1.5 (0.6-4.6)

  1. ¶p < 0.001.
  2. × Calculated as row 3 × row 4.
  3. π calculated as row 3 × row 5.
  4. *p < 0.01.