Table 5 Top scoring adverse events for a class of drugs in this study, which are anti-depressant/ antipsychotic drugs prescribed for neurological problems, across the three different sources
From: A pipeline to extract drug-adverse event pairs from multiple data sources
AERS | BLOGS | BIOMEDICAL LITERATURE | ||||||
|---|---|---|---|---|---|---|---|---|
DRUG | PT | BCPNN Variance | DRUG | EVENT | BCPNN Variance | DRUG | EVENT | BCPNN Variance |
ZIPRASIDONE | TARDIVE DYSKINESIA | 4.2677078217 | BUPROPION | SMOKING | 2.8487222833 | BUPROPION | TOBACCO USE DISORDER | 6.761617438 |
ZIPRASIDONE | DYSTONIA | 4.0558212672 | CARBAMAZEPINE | SEIZURES | 2.1831882505 | OLANZAPINE | SCHIZOPHRENIA | 5.784907952 |
CARBAMAZEPINE | ANTICONVULSANT LEVEL DRUG INCREASED | 3.8394557589 | BUPROPION | INTERACTION | 2.0278154524 | ZIPRASIDONE | SCHIZOPHRENIA | 5.740152197 |
ZIPRASIDONE | EXTRAPYRAMIDAL DISORDER | 3.7617945087 | TRAZODONE | BACK PAIN | 2.0113279316 | CARBAMAZEPINE | TRIGEMINAL NEURALGIA | 5.736653425 |
ZIPRASIDONE | AKATHISIA | 3.6922456683 | OLANZAPINE | DIABETES MELLITUS | 1.96163018 | OLANZAPINE | BIPOLAR DISORDER | 5.711829796 |
OLANZAPINE | HOSPITALISATION | 3.6824877733 | ZIPRASIDONE | VOMITING | 1.9460228686 | OLANZAPINE | PSYCHOMOTOR AGITATION | 5.635398211 |
CARBAMAZEPINE | DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS | 3.5911285749 | BUPROPION | WEIGHT LOSS | 1.9125982688 | PAROXETINE | HAM | 5.635345408 |
ZIPRASIDONE | BRUXISM | 3.3493728888 | OLANZAPINE | OVERWEIGHT | 1.8868082131 | ZIPRASIDONE | QT INTERVAL | 5.621769300 |
OLANZAPINE | LEUKOPENIA | 3.2803137933 | CARBAMAZEPINE | EXANTHEMA | 1.8627395675 | BUPROPION | SUBSTANCE WITHDRAWAL SYNDROME | 5.616013843 |
CARBAMAZEPINE | ANTICONVULSANT DRUG LEVEL ABOVE THERAPEUTIC | 3.2657628102 | ZIPRASIDONE | TREMOR | 1.831079029 | ZIPRASIDONE | BIPOLAR DISORDER | 5.601343825 |