Table 4 Top scoring adverse events for each of the drugs used in this study

1

Aspirin

FLUSHING COLITIS

3.0453446021

HEMORRHAGE

2.2974781367

ANTIPLATELET THERAPY

6.4498501796

COLLAGENOUS

2.967777029

ASTHMA

1.7849414476

ASTHMA, ASPIRIN-INDUCED

6.2465967694

GASTROINTESTINAL ULCER

2.8231226105

ULCER

1.6889750542

PLATELET AGGREGATION

4.9990559736

2

Bupropion

PSORIASIS

3.0858333183

SMOKING

2.8487222833

TOBACCO USE DISORDER

6.7616174378

TINNITUS

3.0003865794

INTERACTION

2.0278154524

SUBSTANCE WITHDRAWAL SYNDROME

5.6160138431

CRYING

2.9716117286

WEIGHT LOSS

1.9125982688

DEPRESSIVE DISORDER, MAJOR

5.0765060025

3

Carbamazepine

ANTICONVULSANT DRUG LEVEL INCREASED

3.8394557589

SEIZURES

2.1831882505

TRIGEMINAL NEURALGIA

5.7366534252

DRUG RASH WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS

3.5911285749

EXANTHEMA

1.8627395675

EPILEPSIES, PARTIAL

5.5948458460

EPILEPSY

3.0298491782

LYMPHOMA

1.4381580775

STEVENS-JOHNSON SYNDROME

5.3815350109

4

Ciprofloxacin

TENDON RUPTURE

4.1146259253

UTI

2.8856797854

MBC

4.6062736746

TENDONITIS

4.0060829925

DIVERTICULITIS

2.2799989819

CROSS RESISTANCE

4.4062217226

TENDON PAIN

3.6892637795

ACNE VULGARIS

1.7510888515

DYSENTERY, BACILLARY

4.3850295544

5

Ibuprofen

KOUNIS SYNDROME

2.9815043448

PAIN

2.3836377566

DUCTUS ARTERIOSUS, PATENT

4.8635855143

TOXIC EPIDERMAL NECROLYSIS

2.8890346654

OSTEOARTHRITIS

1.9773610941

ACUTE PAIN

4.4671583670

OSTEOARTHRITIS

2.8760959875

STOMACH ULCER

1.6554329992

OSTEOARTHRITIS

3.5868790708

6

Morphine

ACUTE CHEST SYNDROME

3.9896519753

HASHIMOTO DISEASE

0.9969507103

POSTOPERATIVE ANALGESIA

5.9041759822

ACCIDENTAL DEATH

3.5380803319

BREATHLESSNESS

0.9969507103

OPIATES

5.8450420720

CARDIO-RESPIRATORY ARREST

3.2009993755

VIOLENT

0.995428479

OPIOID-RELATED DISORDERS

5.4082024508

7

Olanzapine

HOSPITALISATION

3.6824877733

DIABETES MELLITUS

1.96163018

SCHIZOPHRENIA

5.7849079521

LEUKOPENIA

3.2803137933

OVERWEIGHT

1.8868082131

BIPOLAR DISORDER

5.7118297960

METABOLIC SYNDROME

3.1617168832

FEELING COLD

1.4527063824

PSYCHOMOTOR AGITATION

5.6353982109

8

Paroxetine

CONGENITAL ANOMALY

3.1300167523

ANXIETY DISORDERS

1.5594343083

HAM

5.6353454077

ATRIAL SEPTAL DEFECT

3.1224780702

PHOBIC DISORDERS

1.5388697964

DEPRESSIVE DISORDER, MAJOR

5.5424233484

CARDIAC MURMUR

2.9842039722

HOT FLASHES

1.4317963274

PANIC DISORDER

5.3198511794

9

Rosiglitazone

HEART INJURY

1.5296202559

HEART DISEASES

1.9460752101

DIABETES MELLITUS, TYPE 2

5.5082168188

CARDIOVASCULAR DISORDER

1.5209213985

DIABETES MELLITUS

1.6536311321

INSULIN RESISTANCE

5.4173083948

MYOCARDIAL ISCHAEMIA

1.5186640529

CORONARY ARTERY DISEASE

1.564503778

POLYCYSTIC OVARY SYNDROME

4.1594095171

10

Trazodone

CARDIAC ARREST

2.751062765

BACK PAIN

2.0113279316

SLEEP INITIATION AND MAINTENANCE DISORDERS

5.5423900660

COMPLETED SUICIDE

2.4845999228

SLEEP INITIATION AND MAINTENANCE DISORDERS

1.4252916669

PRIAPISM

5.2601858298

SUICIDAL IDEATION

2.3695413431

CONDYLOMATA ACUMINATA

1.3983875588

OVERDOSE

4.5116173724

11

Warfarin

INTERNATIONAL NORMALISED RATIO FLUCTUATION (INCREASED/ DECREASED)

3.1642485602

INTERNATIONAL NORMALIZED RATIO

4.2516503259

VITAMIN K

6.1945919883

CALCIPHYLAXIS

2.8692951662

HEMORRHAGE

2.8983756918

BCR (BLOOD CLOTTING RESPONSE)

5.8376604098

BLUE TOE SYNDROME

2.8692951662

STROKE

2.5276002364

THROMBOEMBOLISM

5.7963964427

12

Ziprasidone

TARDIVE DYSKINESIA

4.2677078217

VOMITING

1.9460228686

SCHIZOPHRENIA

5.7401521972

DYSTONIA

4.0558212672

TREMOR

1.831079029

QT INTERVAL

5.6217692996

EXTRAPYRAMIDAL DISORDER

3.7617945087

PSYCHOTIC DISORDERS

1.6030569698

BIPOLAR DISORDER

5.6013438249