Table 1 Details of the drugs, as indicated by Wang et al. and Leaman et al., used in the current work
From: A pipeline to extract drug-adverse event pairs from multiple data sources
No | Drug name | Drug type | Synonyms | Indications | Known AEs |
|---|---|---|---|---|---|
1 | Bupropion | Atypical anti-depressant and smoking cessation agent | Wellbutrin, Quomen, Zyntabac, Bupropion hydrochloride, Zyban, Amfebutamone, Voxra, Budeprion, Aplenzin | Depression and smoking cessation aid | Dizziness, abnormal sensation, difficulty, drugged state, fatigue, constipation sleeplessness, seizure, tinnitus, pruritus feeling suicidal |
2 | Carbamazepine | Antipsychotic/ anti-depressant | Carbamazepine hydrochloride, Tegretol, Carbazepin, Carbamazepine sulfate (2:1), Carbamazepine dihydrate, Amizepine, Amizepin, Finlepsin, Neurotol, Epitol, Carbamazepine acetate, Carbamazepine phosphate, Biston, Calepsin, Carbatrol, Equetro, Sirtal, Stazepine, Telesmin, EPITAB XR, Teril, Timonil, Trimonil, Epimaz, Carbama, Carbamaze, Carzine, Mazetol, Tegrita, Tegrital, Karbapin, Hermolepsin, Degranol, Tegretal, Mannomustine, Mannitlost, Decranol, Mannitol mustard | Epilepsy, trigeminal neuralgia | Dizziness, somnolence or fatigue, unsteadiness, nausea, vomiting |
3 | Olanzapine | Antipsychotic/ anti-depressant | Zyprexa, Zydis, Relprevv, Zyprexa Relprevv | Schizophrenia, bipolar disorder | Weight gain, alteration in lipids, somnolence or fatigue, increased cholesterol, diabetes |
4 | Ciprofloxacin | Antibiotic | Ciprofloxacin hydrochloride, Ciprinol, Cipro, Baycip, Ciloxan, Ciflox, Cipro XR, Cipro XL, Ciproxin, Prociflor, Proquin, Proquin XR, Ciprex, Cetraxal, Axcin | Bacterial infection | Diarrhea, vomiting, abdominal pain, headache, restlessness |
5 | Trazadone | Antipsychotic/anti-depressant | Trazon, Thombran, Trazodone hydrochloride, Gen trazodone, Trazodon neuraxpharm, Molipaxin, Apo trazodone, Trittico, Deprax, Novo trazodone, Pms-trazodone, Nu-trazodone, Nu trazodone, Desyrel, Oleptro, Beneficat, Desirel, Trazorel, Trialodine, Mesyrel | Depression | Somnolence or fatigue, headache, dry mouth, dizziness, nausea |
6 | Ziprasidone | Antipsychotic/anti-depressant | Ziprasidone hydrochloride, ziprasidone hydrochloride, monohydrate, Geodon, Ziprazidone, Zeldox | Schizophrenia | Somnolence or fatigue, dyskinesia, nausea, constipation, dizziness |
7 | Aspirin | Analgesic/anti-inflammatory | Zorprin, Magnecyl, Acetylsalicylic acid, Polopirin, Solupsan, Endosprin, Polopiryna, Acetysal, Easprin, Ecotrin, Aloxiprimum, Colfarit, Dispril, Solprin, Micristin, Acylpyrin, Empirin, Bufferin, Fasprin, Genacote, Halfprin | Pain, fever, reduce blood clotting | Nausea, vomiting, ulcers, bleeding, stomach pain or upset |
8 | Ibuprofen | Analgesic/anti-inflammatory | Salprofen, Trauma-dolgit gel, Trauma dolgit gel, Rufen, Nuprin, Brufen, Motrin, Ibumetin, Nurofen, Advil | Pain of rheumatoid arthritis, osteoarthritis, menstrual cramps, or mild to moderate pain | Headache, achalasia, nausea, constipation |
9 | Warfarin | Anticoagulant | Coumadine, Tedicumar, Warfant, Coumadin, Gen-warfarin, Aldocumar, Marevan, Apo-warfarin, Jantoven, Lawarin, Waran | - | - |
10 | Paroxetine | Antipsychotic/ anti-depressant | Seroxat, Paroxetine maleate, Paxil, Aropax, Paroxetine acetate, Paroxetine hydrochloride, Paxil cr, Pexeva, Sereupin | Mental depression, obsessive-compulsive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder | Pain chest, drowsiness, orthostasis, dyspnea, agitation, dizziness, feeling suicidal |
11 | Rosiglitazone | Antidiabetic | Avandia, Rosiglitazone maleate, | Diabetes | Headache, chest pain, left atrial hypertrophy, shortness of breath |
12 | Morphine | Analgesic/anti-inflammatory | Morphia, Oramorph SR, Duramorph, Morphine chloride, Morphine sulfate, Ms contin, Mir, Morin, Nepenthe, Mirs, Micro-rna, Avinza, Kadian, Morphine ir, Msir, Roxanol, Infumorph, Kapabloc, Kapanol, Loceptin, Longphine, Malfin, Maxidon, Meconium, Meslon, Micro-morphine, Mogetic, Morapid, Moraxen, Morcap, Moretal, Morfenil, Morficontin, Morfin, Morfin meda, Morfina, Morph, Morphanton, Morphex, Morphgesic, Morphin, Morphini, Morphinum, Morphiphar, Morphitec, Morphium, Morstel, Mos, Moscontin, Morstel, Mortificontin, Ms direct, Ms long, Ms mono, Mst continus, Mst unicontinus, Mundidol, Mxl, Neocalmans, Noceptin, Oblioser, Oglos, Oms concentrate Onkomorphin, Opitard, Opsalvina, Oramorph, Ordine, Relimal, Relipain, Repriadol, Rescudose, Sevredol, Skenan, Slovalgin, Srm-rhotard, Statex, Stellaphine, Stellorphinad, Stellorphine, Substitol, Vendal, Zomorph | - | - |