Skip to main content

Table 4 Pathway functional modules from SNP combination.

From: Finding type 2 diabetes causal single nucleotide polymorphism combinations and functional modules from genome-wide association data

Functional Module Name Category # of genes # of genes in functional module p-value FDR
Focal adhesion KEGG 6 175 3.144E-03 7.982E-03
Hemostasis Reactome 6 207 7.080E-03 1.091E-02
ErbB1 downstream signaling NCI-Nature 4 101 9.465E-03 1.662E-02
Endometrial cancer KEGG 3 48 7.073E-03 1.755E-02
Formation of Platelet plug Reactome 4 106 1.116E-02 1.840E-02
PDGF signaling pathway PANTHER 4 108 1.190E-02 2.053E-02
Viral myocarditis KEGG 3 54 9.792E-03 2.506E-02
BCR signaling pathway NCI-Nature 3 63 1.487E-02 2.703E-02
amine and polyamine degradation UniPathway 1 4 3.236E-02 3.236E-02
Rho GTPase cycle Reactome 3 73 2.196E-02 3.420E-02
Regulation of RAC1 activity NCI-Nature 2 26 1.900E-02 3.498E-02
Signaling by Rho GTPases Reactome 3 73 2.196E-02 3.633E-02
Thrombin-mediated activation of PARs Reactome 1 3 2.437E-02 3.841E-02
Fc epsilon RI signaling pathway KEGGM 3 63 1.487E-02 4.051E-02
EGF receptor (ErbB1) signaling pathway NCI-Nature 4 132 2.313E-02 4.096E-02