Table 4 Pathway functional modules from SNP combination.
Functional Module Name | Category | # of genes | # of genes in functional module | p-value | FDR |
|---|---|---|---|---|---|
Focal adhesion | KEGG | 6 | 175 | 3.144E-03 | 7.982E-03 |
Hemostasis | Reactome | 6 | 207 | 7.080E-03 | 1.091E-02 |
ErbB1 downstream signaling | NCI-Nature | 4 | 101 | 9.465E-03 | 1.662E-02 |
Endometrial cancer | KEGG | 3 | 48 | 7.073E-03 | 1.755E-02 |
Formation of Platelet plug | Reactome | 4 | 106 | 1.116E-02 | 1.840E-02 |
PDGF signaling pathway | PANTHER | 4 | 108 | 1.190E-02 | 2.053E-02 |
Viral myocarditis | KEGG | 3 | 54 | 9.792E-03 | 2.506E-02 |
BCR signaling pathway | NCI-Nature | 3 | 63 | 1.487E-02 | 2.703E-02 |
amine and polyamine degradation | UniPathway | 1 | 4 | 3.236E-02 | 3.236E-02 |
Rho GTPase cycle | Reactome | 3 | 73 | 2.196E-02 | 3.420E-02 |
Regulation of RAC1 activity | NCI-Nature | 2 | 26 | 1.900E-02 | 3.498E-02 |
Signaling by Rho GTPases | Reactome | 3 | 73 | 2.196E-02 | 3.633E-02 |
Thrombin-mediated activation of PARs | Reactome | 1 | 3 | 2.437E-02 | 3.841E-02 |
Fc epsilon RI signaling pathway | KEGGM | 3 | 63 | 1.487E-02 | 4.051E-02 |
EGF receptor (ErbB1) signaling pathway | NCI-Nature | 4 | 132 | 2.313E-02 | 4.096E-02 |