Skip to main content

Advertisement

Table 1 Comparison of the demographic and clinical characteristics of the COPD patients with very poor or typical HRQoL measured with the generic 15D instrument

From: Bayesian predictors of very poor health related quality of life and mortality in patients with COPD

Characteristics Very poor HRQoL N = 152 Typical HRQoL N = 587 P value
Male gender, N (%)1 93 (61.2) 377 (65.1) 0.4
Age, mean in years (±SD) 2 63.6 (7.0) 64.1 (6.8) 0.3
Duration of COPD, mean in years (±SD) 2 6.4 (4.3) 5.3 (5.0) 0.002
Age at asthma onset, mean in years (±SD) 2 52.8 (7.3) 57.6 (7.3) 0.002
Age at COPD onset, mean in years (±SD) 2 57.6 (7.6) 58.4 (7.3) 0.2
Pack years, mean (±SD) 2 49 (19) 51 (20) 0.4
DLcCOVA % of predicted, mean (±SD) 2 74 (23) 77 (22) 0.3
Baseline spirometry 2    
FEV1% of predicted 52.5 (21.1) 58.4 (18.0) <0.0001
FVC% of predicted 68.1 (19.0) 76.2 (17.6) <0.0001
FEV1/FVC of predicted, mean (±SD) 61.6 (15.7) 61.5 (13.4) 0.7
Spirometry after bronchodilatation 2    
FEV1% of predicted 57.7 (20.3) 61.7 (16.8) 0.04
FVC% of predicted 71.5 (17.9) 79.1 (16.9) <0.0001
FEV1/FVC of predicted, mean (±SD) 64.3 (14.8) 62.9 (13.2) 0.2
Proportion (%) of patients at GOLD 1    
  former stage 0: FEV1≥80% 11.2 9.5  
  stage 1: FEV1/FVC<70%, FEV1≥80% 1.0 3.0  
  stage 2: FEV1/FVC<70%, 50%≤FEV1<80% 24.5 40.4  
  stage 3: FEV1/FVC<70%, 30%≤FEV1<50% 18.4 18.0  
  stage 4: FEV1/FVC<70%, FEV1<30% 9.2 4.3  
  stage undefined: FEV1/FVC≥70%, FEV1<80% 35.7 24.8 0.02
Proportion (%) of patients with home oxygen therapy 8.6 1.7 <0.0001
In severe COPD (FEV1<50% of predicted) 2    
Arterial O2 pressure, mean (±SD) 9.0 (1.5) 9.7 (14) 0.006
Arterial CO2 pressure, mean (±SD) 5.5 (0.9) 5.3 (0.5) 0.4
Proportion (%) of deaths during follow-up1 9.9 5.5 0.05
HRQL scores, mean (±SD) 2    
Airway-specific (range 20–0) 13.0 (3.6) 6.9 (4.5) <0.0001
Generic (range 0–1) 0.63 (0.06) 0.83 (0.07) <0.0001
Proportion (%) of patients 1    
Underweight BMI < 20 1.4 3.1  
Normal weight BMI 20–25 33.6 41.2  
Overweight BMI 25–30 53.6 50.1  
Obese BMI > 30 11.4 5.6 0.04
Proportion (%) of patients with co-commitant 1    
  Coronary disease 27.0 20.2 0.07
  Cerebrovascular disease 12.5 6.2 0.009
  Cardiovascular disease 37.5 25.6 0.004
  Diabetes 25.7 12.4 <0.0001
  Peripheral artery occlusive disease 3.9 4.7 0.7
  Metabolic syndrome 32.9 19.0 0.001
  Alcohol abuse 21.7 13.3 0.01
  Psychiatric condition 17.8 8.3 0.001
  Hypertension 46.7 39.0 0.09
  1. 1Chi-square test, 2Mann-Whitney U test.