Skip to main content

Table 2 Spot check of NSCLC genes/proteins for their relevance to biomarker applicability and evidence

From: Mining biomarker information in biomedical literature

Gene or protein

No. of retrieved document

Relative entropy rank

Frequency based rank

Example PMID

Biomarker applicability

Biomarker evidence

P53

281

1

1

20521348

Prognosis

Expression

VEGFA

128

6

4

21964530

Prognosis

Expression

BCL2

90

8

6

19560836

Survival

Expression

PCNA

47

11

10

21495034

Prognosis

Expression

VEGFC

22

16

21

19758816

Recurrence

Expression

PTGS2

33

25

15

20592629

Survival

Expression

CDKN1B

12

50

52

15483027

Prognosis

Expression

DNAJB4

2

100

344

16788156

Survival

Expression

CDK2

5

342

112

10817513

Prognosis

No impact

  1. For the SCAIView search the MeSH disease “Carcinoma, Non-Small-Cell Lung” in combination with five biomarker retrieval classes (omitting the class Antecedent) were selected and the retrieved genes were ranked according the Relative Entropy or frequency. In spot tests the abstracts were analysed for containing biomarker information for the respective genes.