Figure 2

Visual aid illustrating two adjuvant treatment scenarios for patients with UICC stages II and III colon cancer [[14]] . The results of an operation (OP) plus 5-FU chemotherapy (CHT) are shown as mild treatment (A) on the left, and the results of an OP plus 5-FU and oxaliplatin combination CHT are shown as intense treatment (B) on the right. The relative incidence of death, local recurrence and distant metastasis are displayed in the two upper quadrants and important undesired events in the two lower quadrants. The difference of recurrence of the two treatment options is summarized in the central dotted circle followed by a statement about overall survival benefit.