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Table 2 Reduction in cardiovascular event rate by traditional antihypertensive medications in a hypothetical population

From: Antihypertensive medication versus health promotion for improving metabolic syndrome in preventing cardiovascular events: a success rate-oriented simulation study

k = 20

a = 130 mm Hg

a = 140 mm Hg

a = 150 mm Hg

a = 160 mm Hg

 

b = 0.05

b = 0.03

b = 0.02

b = 0.01

 

c = 130 mm Hg

c = 140 mm Hg

c = 150 mm Hg

c = 160 mm Hg

 

d = 0.8

d = 0.7

d = 0.6

d = 0.5

e = 140 mm Hg

2.33 × 10-3

   

e = 150 mm Hg

2.08 × 10-3

9.99 × 10 -4

  

e = 160 mm Hg

1.56 × 10-3

8.46 × 10 -4

4.52 × 10 -4

 

e = 180 mm Hg

4.51 × 10-4

3.02 × 10-4

1.92 × 10-4

6.64 × 10-5

k = 30

a = 130 mm Hg

a = 140 mm Hg

A = 150 mm Hg

a = 160 mm Hg

 

b = 0.05

b = 0.03

b = 0.02

b = 0.01

 

c = 130 mm Hg

c = 140 mm Hg

c = 150 mm Hg

c = 160 mm Hg

 

d = 0.8

d = 0.7

d = 0.6

d = 0.5

e = 140

1.13 × 10-3

   

e = 150

9.68 × 10-4

4.24 × 10 -4

  

e = 160

6.74 × 10-4

3.42 × 10 -4

1.76 × 10 -4

 

e = 180

1.58 × 10-4

1.01 × 10-4

6.26 × 10-5

2.06 × 10-5

k = 40

a = 130 mm Hg

a = 140 mm Hg

A = 150 mm Hg

a = 160 mm Hg

 

b = 0.05

b = 0.03

b = 0.02

b = 0.01

 

c = 130

c = 140

c = 150

c = 160

 

d = 0.8

d = 0.7

d = 0.6

d = 0.5

e = 140

7.32 × 10-4

   

e = 150

6.14 × 10-4

2.58 × 10 -4

  

e = 160

4.11 × 10-4

2.02 × 10 -4

1.02 × 10 -4

 

e = 180

8.66 × 10-5

5.40 × 10-5

3.31 × 10-5

1.06 × 10-5

  1. Abbreviations: k = constant determining the slope of the exponential curve between systolic blood pressure and cardiovascular incidence rate; l = constant related to absolute value of cardiovascular incidence rate of 100; m = constant determining the slope of the exponential curve to be e0/l of 140; a = an alarming SBP of 130, 140, 150, and 160 mm Hg, above which patients should be concerned about their BP; b = an accessibility factor to a primary physician of 0.05, 0.03, 0.02, and 0.01; c = the target SBP level of 130, 140, 150, and 160 mm Hg; d = adherence for reaching the target SBP level of 0.5, 0.6, 0.7, and 0.8; e = SBP level of 140, 150, 160, or 180 mm Hg from which administration of antihypertensive medications was initiated.