| Prepubertal years | Total pubertal growth | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | 1st year | 2nd year | 3rd year | 4th year (@) |  | male (@) | female (@) | ||||||
Parameter | Â | Â | Â | Â | Â | Â | Â | Â | Parameter | Â | Â | Â | Â |
N | 613 | Â | 385 | Â | 317 | Â | 180 | Â | Â | 355 | Â | 221 | Â |
R2 | 0.52 | Â | 0.34 | Â | 0.33 | Â | 0.30 | Â | Â | 0.66 | Â | 0.65 | Â |
Error SD (cm) | 1.3 | Â | 1.1 | Â | 1.0 | Â | 1.0 | Â | Â | 4.5 | Â | 3.8 | Â |
Parameter estimate (PE) | PE | Rank | PE | Rank | PE | Rank | PE | Rank | Â | PE | Rank | PE | Rank |
Intercept (constant) | 9.4 | Â | 4.7 | Â | 6.2 | Â | 6.0 | Â | Intercept | 72.6 | Â | 57.0 | Â |
Age at start (years) | -0.31 | 2 | -0.11 | 2 | -0.18 | 2 | -0.05 | 4 | Age puberty onset (years) | -4.0 | 1 | -3.7 | 1 |
Weight at start (SDS) | 0.30 | 3 | - | - | 0.19 | 3 | 0.40 | 1 | Age - Bone age (years) | 1.4 | 2 | 1.7 | 2 |
GH dose at year start (mg/kg/day) | 56.51 | 1 | 13.46 | 3 | 1.21# | 5 | 0.87& | 3 | Mean GH dose (mg/kg/week) | 8.8 | 4 | 9.5 | 4 |
MPH (SDS) | 0.11 * | 4 | - | - | 0.12$ | 4 | - | - | Height - MPH $ (SDS) | -1.3 | 3 | -1.2 | 3 |
HV in previous year (cm/year) | - | - | 0.30 | 1 | 0.26 | 1 | 0.21 | 2 | _ | _ | _ | _ | _ |