|
1st prepubertal year
|
2nd prepubertal year
|
---|
|
N
|
Mean
|
SD
|
N
|
Mean
|
SD
|
---|
At GH treatment start
| | | | | | |
Sex male %
| |
67
| | |
62
| |
Birth weight SDS
|
613
|
-2.7
|
1.0
|
385
|
-2.6
|
1.0
|
Birth length SDS
|
465
|
-2.7
|
1.3
|
295
|
-2.7
|
1.3
|
Maximum GH peak (ng/ml)
|
613
|
20.8
|
13.3
|
385
|
20.9
|
13.6
|
MPH SDS
|
607
|
-0.9*
|
1.2
|
379
|
-0.8*
|
1.2
|
Age (years)
|
613
|
6.6
|
2.5
|
385
|
6.3
|
2.2
|
Height SDS
|
613
|
-2.8*
|
0.9
|
385
|
-2.8*
|
0.9
|
Weight SDS
|
613
|
-3.4
|
1.6
|
385
|
-3.4
|
1.6
|
GH dose (mg/kg/day)
|
613
|
0.04
|
0.02
|
385
|
0.04
|
0.02
|
First-year growth response
| | | | | | |
HV(cm/year)
|
613
|
8.6
|
1.9
|
385
|
8.7
|
1.8
|
Change in (delta) height SDS
|
613
|
0.7*
|
0.4
|
385
|
0.7*
|
0.3
|
Second year growth response
| | | | | | |
HV(cm/year)
| | | |
385
|
7.0
|
1.4
|
Change in (delta) height SDS
| | | |
385
|
0.3*
|
0.2
|
- The first and second pre-pubertal years on GH [4] are shown.
- * = calculations based on Tanner's references [8]