| 1st prepubertal year | 2nd prepubertal year | ||||
---|---|---|---|---|---|---|
 | N | Mean | SD | N | Mean | SD |
At GH treatment start | Â | Â | Â | Â | Â | Â |
   Sex male % |  | 67 |  |  | 62 |  |
   Birth weight SDS | 613 | -2.7 | 1.0 | 385 | -2.6 | 1.0 |
   Birth length SDS | 465 | -2.7 | 1.3 | 295 | -2.7 | 1.3 |
   Maximum GH peak (ng/ml) | 613 | 20.8 | 13.3 | 385 | 20.9 | 13.6 |
   MPH SDS | 607 | -0.9* | 1.2 | 379 | -0.8* | 1.2 |
   Age (years) | 613 | 6.6 | 2.5 | 385 | 6.3 | 2.2 |
   Height SDS | 613 | -2.8* | 0.9 | 385 | -2.8* | 0.9 |
   Weight SDS | 613 | -3.4 | 1.6 | 385 | -3.4 | 1.6 |
   GH dose (mg/kg/day) | 613 | 0.04 | 0.02 | 385 | 0.04 | 0.02 |
First-year growth response | Â | Â | Â | Â | Â | Â |
   HV(cm/year) | 613 | 8.6 | 1.9 | 385 | 8.7 | 1.8 |
   Change in (delta) height SDS | 613 | 0.7* | 0.4 | 385 | 0.7* | 0.3 |
Second year growth response | Â | Â | Â | Â | Â | Â |
   HV(cm/year) |  |  |  | 385 | 7.0 | 1.4 |
   Change in (delta) height SDS |  |  |  | 385 | 0.3* | 0.2 |