Table 4 Voluntarily reported adverse drug events pre- and post-deployment of the pediatric Advanced Dosing Model
Unit | Pre-ADM | Post-ADM |
|---|---|---|
PICU | Â | Â |
   No. events | 421 | 410 |
   No. ADEs | 53 | 31 |
   % ADEs (CI) | 12.6 (9.4-15.8) | 7.5 (5.0-10.1) |
   % change (p value) | -39.9 (0.016*) | |
   No. patient days | 14,027 | 14,370 |
   ADEs per 1000 patient days (CI) | 3.8 (2.8-4.8) | 2.2 (1.4-3.0) |
   % change (p value) | -42.9 (0.012*) | |
NICU | Â | Â |
   No. events | 567 | 272 |
   No. ADEs | 75 | 23 |
   % ADEs (CI) | 13.2 (10.4-16.0) | 8.5 (5.2-11.8) |
   % change (p value) | -36.1 (0.044*) | |
   No. patient days | 45,627 | 26,122 |
   ADEs per 1000 patient days (CI) | 1.6 (1.2-2.0) | 0.9 (0.5-1.3) |
   % change (p value) | -46.4 (0.006*) | |