Table 3 Dosing regions for several ampicillin indications

Bone marrow transplant

≤29 days

< 8

100 mg/kg/dose IV q8h

≥8

100 mg/kg/dose IV q8 h up to a max single dose of 1 g

NICU, transitional care

≤7 days

any

100 mg/kg/dose IV/IM q8 h (equivalent to 300 mg/kg/day)

≥8

any

75 mg/kg/dose IV q6 h (approx. 300 mg/kg/day)

PICU, cardiac ICU

≤29 days

≥8

100 mg/kg/dose IV q8 h up to a max single dose of 1 g

Any

100 mg/kg/dose IV q8h

General care

≥14 yrs

< 27

75 mg/kg/dose IV q6h

≥27

2 g IV q6h

Non-pediatric location

≤7 days

≥9

100 mg/kg/dose IV q8 h up to a max single dose of 1 g

< 9

100 mg/kg/dose IV q8h

8 days-14 yrs

< 27

75 mg/kg/dose IV q6h

≥27

2 g IV q6h

14-18 yrs

≥27 & <45

2 g IV q6h

< 27

75 mg/kg/dose IV q6h

Any location - dosing region scenarios defined by order set use

≥0 days

< 20

50 mg/kg q6 h × 4 doses

≥20

1 g q6 h × 4 doses

Any location - dosing region scenarios defined by order set use

≥0 days

< 20

50 mg/kg ONCALLPRN* to OR

≥20

1 g ONCALLPRN* to OR