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Table 1 Demographic and clinical characteristics of the included patients

From: Predictive model and risk analysis for coronary heart disease in people living with HIV using machine learning

Variables

All

(n = 6772)

non-CHD

(n = 6533)

CHD

(n = 239)

P-Value

Age, years

 

54(43–64)

53(43–64)

67(60–74)

< 0.001

Sex

Male

5152

4955

197

0.019

Female

1620

1578

42

Ethnicity

Han

3327

3199

128

0.12

Zhuang

2994

2892

102

Others

451

422

9

Marital status

Unmarried

1748

1719

29

< 0.001

Married

3405

3650

155

Divorce

/widowhood

1119

1164

55

Hypertention

Yes

451

391

60

< 0.001

Diabetes

Yes

262

235

27

< 0.001

COPD

Yes

152

131

21

< 0.001

Heart failer

Yes

323

244

79

< 0.001

CD4 count, cell/µL

 

72(16–215)

69(15–212)

137(35–255)

< 0.001

CD45count, cell/µL

 

786.25(412-1284.75)

784(407-1280.50)

891(501–1359)

0.022

CD8 count, cell/µL

 

379(202–639)

379(202–638)

379(232–665)

0.517

D-Dimer, mg/L

 

1.79(0.6–5.2)

1.81(0.60–5.24)

1.50(0.57–3.78)

0.047

CD3 count, cell/µL

 

520(259-886.75)

517(256–880)

607(321–958)

0.030

ALB, U/L

 

32.60(27.37–37.20)

32.60(27.30–37.20)

32.20(27.80–36.70)

0.763

WBC, 10^9/L

 

4.89(3.31–6.92)

4.87(3.29–6.90)

5.22(3.70–7.08)

0.033

APTT, s

 

30.20(25-41.40)

30.20(25-41.80)

28.90(23.70–35.70)

0.003

MONO, 10^9/L

 

0.47(0.31–0.66)

0.47(0.31–0.65)

0.52(0.35–0.70)

0.019

LDL-c, mmol/L

 

2.01(1.52–2.57)

2.01(1.52–2.56)

2.05(1.60–2.63)

0.156

AMY, U/L

 

90.77(69–117)

90.75(69-117.41)

91.74(67–112)

0.304

Ca, mmol/L

 

2.06(1.93–2.17)

2.06(1.93–2.17)

2.05(1.92–2.15)

0.646

TG, mmol/L

 

1.42(1.04–2.02)

1.42(1.04–2.03)

1.34(1.03–1.84)

0.057

HDL-c, mmol/L

 

0.85(0.60–1.11)

0.84(0.59–1.11)

0.91(0.69–1.13)

0.006

GGT, U/L

 

63(35–121)

63(35–121)

61(33–121)

0.508

ALT, U/L

 

22(13–37)

22(13–37)

20(14–37)

0.842

AST/ALT

 

1.38(0.94–2.09)

1.39(0.93–2.09)

1.33(1-1.93)

0.847

AST, U/L

 

27(20–44)

27(20–44)

27(20–46)

0.721

Cys-C, mg/L

 

1.17(0.98–1.54)

1.17(0.98–1.54)

1.27(1.01–1.72)

0.010

RBC, 10^12/L

 

3.41(2.77–4.02)

3.40(2.77–4.02)

3.47(2.79–4.03)

0.554

RDW-CV

 

15(13.97-18)

15.25(13.96-18)

15(14–17)

0.031

RDW-SD

 

49(44–57)

49(44–57)

49(44–55)

0.369

HCT

 

31(25.70–35.50)

30.90(25.70–35.50)

31.80(26.60–35.80)

0.217

Scr, µmol/L

 

70(58–88)

70(57–88)

78(66–106)

< 0.001

Ccr, mL/min

 

64.36(47.86–77.67)

64.36(47.86–77.67)

58.95(42.40-75.23)

0.010

CK, U/L

 

65(39-110.90)

65(39-110.66)

67.70(42–115)

0.169

K, mmol/L

 

3.7(3.30–4.10)

3.70(3.30–4.10)

3.70(3.40–4.18)

0.143

I-Bil, µmol/L

 

3.72(2.50–5.79)

3.73(2.50–5.80)

3.59(2.50–5.43)

0.375

LYM, 10^9/L

 

0.98(0.56–1.53)

0.97(0.56–1.52)

1.13(0.67–1.56)

0.015

Cl, mmol/L

 

102.90(100–106)

102.90(100–106)

102.90(100–106)

0.274

Mg, mmol/L

 

0.78(0.71–0.87)

0.78(0.71–0.86)

0.78(0.71–0.85)

0.788

Na, mmol/L

 

137(133–139)

137(133–139)

136(132–140)

0.377

UREA, mmol/L

 

4.15(3.10–5.90)

4.10(3.10–5.90)

4.70(3.60–6.90)

< 0.001

SUA, µmol/L

 

300(221–398)

300(221–396)

319(233–443)

0.005

TT, s

 

19.60(18.20–22.30)

19.60(18.20–22.30)

19.60(18.30–21.60)

0.566

PT, s

 

12.20(11.10–15)

12.20(11.10–15.10)

11.90(10.80–13.60)

0.021

MCV, fL

 

90.10(83.70–96.40)

90(83.70–96.30)

90.60(84-98.80)

0.064

MCH, pg

 

29.90(27.40–32.30)

29.90(27.40–32.20)

30.40(27.40–33)

0.052

MCHC, g/L

 

331(319–342)

331(319–342)

331(319–341)

0.865

MPV, fL

 

9.90(9.20–10.60)

9.90(9.20–10.60)

9.80(9.30–10.60)

0.769

Glu, mmol/L

 

6.70(5.41-8)

6.70(5.40-8)

7.30(5.80–9.30)

< 0.001

PA, mg/L

 

168(101–235)

168(101–235)

169(123–226)

0.426

Glb, g/L

 

35.90(30.40–42.30)

35.90(30.40–42.40)

32.60(30.42–40.90)

0.657

LDH, U/L

 

228(180-313.65)

228(180–314)

224(185–296)

0.892

BASO, 10^9/L

 

0.02(0.01–0.03)

0.02(0.01–0.03)

0.02(0.01–0.03)

0.353

EOS, 10^9/L

 

0.10(0.02–0.24)

0.10(0.02–0.24)

0.10(0.02–0.23)

0.474

Fbg, g/L

 

3.02(1.84–4.11)

3.01(1.84–4.11)

3.10(2.12–4.26)

0.143

Hb, g/L

 

102(84–119)

102(83.31-118.63)

105(87.60–120)

0.103

D-Bil, µmol/L

 

2.89(1.75–5.31)

2.89(1.74–5.30)

2.88(1.89–5.50)

0.771

NEUT, 10^9/L

 

2.93(1.85–4.69)

2.93(1.84–4.69)

3.14(2.05–4.77)

0.110

TC, mmol/L

 

3.62(2.88–4.42)

3.62(2.87–4.42)

3.61(2.98–4.41)

0.468

T-Bil, µmol/L

 

6.90(4.60–11)

6.90(4.60-11.03)

7.14(4.63–10.46)

0.821

TP, g/L

 

68.90(62.40–75.40)

69(62.40–75.40)

68(62.30–74.60)

0.175

  1. The continuous variables were expressed as median the median (IQR) after the normality distribution test. The categorical variables were expressed as number (percentage). ALB, albumin; WBC, white blood cell; APTT, activated partial prothrombin time; MONO, monocyte count; LDL-c, low density lipoprotein cholesterol; AMY, amylase; Ca, calcium; TG, triglyceride; HDL-c, high density lipoprotein cholesterol; GGT, γ-Glutamyl Transferase; ALT, alaninetransaminase; AST, aspartate aminotransferase; Cys-C, Cystatin C; RBC, red blood cell; RDW-CV, red blood cell distribution width CV; RDW-SD, red blood cell distribution width SD; HCT, hematocrit; Scr, serum creatinine; Ccr, creatinine clearance rate; CK, creatine kinase; K, kalium; I-Bil, indirect bilirubin; LYM, Lymphocyte count; Cl, chlorine; Mg, magnesium; Na, sodium; SUA, serum uric acid; TT, thrombin time; PT, prothrombin time; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MPV, mean platelet volume; Glu, blood glucose; PA, prealbumin; Glb, globulin; LDH, lactate dehydrogenase; BASO, basophil count; EOS, eosinophil count; Fbg, fibrinogen; Hb, hemoglobin; D-Bil, direct bilirubin; NEUT, neutrophil count; TC, total cholesterol; T-Bil, total bilirubin; TP, total Protein