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Table 5 Subgroup analysis based on intestine disease status

From: Effect of early serum phosphate disorder on in-hospital and 28-day mortality in sepsis patients: a retrospective study based on MIMIC-IV database

Outcome

Delta serum phosphate level during the first 3 days of ICU admission (mg/dL)

 

0−1.3

1.4−2.0

2.1–3.1

≥ 3.2

Intestine disease during hospitalization(n = 200)

N

35

52

73

40

In-hospital mortality

5 (14.29)

9 (17.31)

19 (26.03)

13 (32.50)

Mortality, OR (95% CI, P)

    

-Model 1, unadjusted

1.0 (Ref)

1.26 (0.39,4.43), 0.707

2.11 (0.76,6.88), 0.176

2.89 (0.95,9.99), 0.072

-Model 2a

1.0 (Ref)

1.01 (0.31,3.64), 0.989

2.20 (0.77,7.28), 0.161

3.41 (1.09,12.2), 0.043

-Model 3b

1.0 (Ref)

0.87 (0.25,3.25), 0.826

1.91 (0.63,6.65), 0.271

2.87 (0.84,11.0), 0.104

28-day mortality

9 (25.71)

10 (19.23)

22 (30.14)

18 (45.00)

Mortality, OR (95% CI, P)

    

-Model 1, unadjusted

1.0 (Ref)

0.69 (0.25,1.94), 0.474

1.25 (0.51,3.20), 0.635

2.36 (0.90,6.52), 0.086

-Model 2a

1.0 (Ref)

0.57 (0.20,1.65), 0.296

1.24 (0.50,3.23), 0.645

2.71 (1.01,7.69), 0.052

-Model 3b

1.0 (Ref)

0.60 (0.19,1.86), 0.368

1.24 (0.46,3.54), 0.677

2.94 (0.97,9.50), 0.061

No intestine disease during hospitalization(n = 1175)

N

258

303

297

317

In-hospital mortality

65 (25.19)

91 (30.03)

85 (28.62)

116 (36.59)

Mortality, OR (95% CI, P)

    

-Model 1, unadjusted

1.0 (Ref)

1.27 (0.88,1.86), 0.203

1.19 (0.82,1.74), 0.365

1.71 (1.20,2.47), 0.004

-Model 2a

1.0 (Ref)

1.31 (0.90,1.92), 0.156

1.23 (0.84,1.80), 0.289

1.87 (1.29,2.70), < 0.001

-Model 3b

1.0 (Ref)

1.29 (0.88,1.92), 0.196

1.19 (0.80,1.79), 0.386

1.54 (1.02,2.36), 0.043

28-day mortality

80 (31.01)

112 (36.96)

97 (32.66)

132 (41.64)

Mortality, OR (95% CI, P)

    

-Model 1, unadjusted

1.0 (Ref)

1.30 (0.92,1.86), 0.139

1.08 (0.75,1.55), 0.677

1.59 (1.13,2.25), 0.009

-Model 2a

1.0 (Ref)

1.36 (0.95,1.95), 0.092

1.11 (0.77,1.60), 0.564

1.74 (1.23,2.49), 0.002

-Model 3b

1.0 (Ref)

1.32 (0.91,1.91), 0.146

1.04 (0.71,1.54), 0.825

1.36 (0.91,2.04), 0.136

  1. a: Adjusted for sex and age
  2. b: Adjusted for sex, age, infection site, AKI, invasive mechanical ventilation time, APACHEII score, PH, creatinine