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Table 6 Data characteristics analysis of the infected group and non-infected group(n = 512)

From: Prediction of postoperative infectious complications in elderly patients with colorectal cancer: a study based on improved machine learning

Variables

Training sets

 

Validation set

 

Infection group (n = 87)

Non-infected

group (n = 271)

P

Infection group

(n = 38)

Non-infected

group (n = 116)

P

Gender

  

0.06

  

0.09

 Male

57(0.66)

147(0.54)

 

18(0.47)

73(0.63)

 

 Female

30(0.34)

124(0.46)

 

20(0.53)

43(0.37)

 

Body Mass

Index (kg/m2)

22.02(3.54)

21.88(3.56)

0.769

21.33(3.66)

21.89(3.58)

0.458

ASA

  

< 0.001

  

0.001

 I

10(0.11)

13(0.05)

 

6(0.16)

10(0.09)

 

 II

34(0.39)

179(0.66)

 

17(0.45)

88(0.76)

 

 III

43(0.50)

79(0.29)

 

15(0.39)

18(0.15)

 

Tumor size

(cm)

4.57(1.78)

4.58(1.94)

0.987

4.86(2.16)

4.93(1.87)

0.865

T-stage

      

 T1–2

26(0.30)

78(0.29)

0.844

14(0.37)

39(0.34)

0.717

 T3–4

61(0.70)

193(0.71)

 

24(0.63)

77(0.66)

 

N-stage

      

 N-

57(0.66)

159(0.59)

0.256

28(0.74)

81(0.70)

0.650

 N+

30(0.34)

112(0.41)

 

10(0.26)

35(0.30)

 

TNM stage

  

0.282

  

0.73

 I

22(0.25)

65 (0.24)

 

9(0.24)

35 (0.30)

 

 II

36(0.41)

91 (0.34)

 

16 (0.42)

43(0.37)

 

 III

29 (0.34)

115 (0.42)

 

13 (0.34)

38 (0.33)

 

Operative time (h)

4.12(1.38)

3.42(1.18)

< 0.001

4.07(1.73)

3.38(1.14)

0.008

Blood loss (ml)

128.42(143.36)

109.53(103.54)

0.43

187.74(235.74)

143.21(163.92)

023

Smoking

  

0.847

  

0.707

 Yes

5(0.06)

15(0.06)

 

4(0.11)

8(0.07)

 

 No

82(0.94)

256(0.94)

 

34(0.89)

108(0.93)

 

Chronic lung disease

  

0.007

  

0.003

 Yes

19(0.22)

20(0.07)

 

11(0.29)

11(0.09)

 

 No

68(0.78)

251(0.93)

 

27(0.71)

105(0.91)

 

Hypertension

  

0.458

  

0.306

 Yes

33(0.38)

115(0.42)

 

20(0.53)

50(0.43)

 

 No

54(0.62)

156(0.58)

 

18(0.47)

66(0.57)

 

Diabetes

  

< 0.001

  

0.003

 Yes

19(0.22)

18(0.07)

 

10(0.26)

8(0.07)

 

 No

68(0.78)

253(0.93)

 

28(0.74)

108(0.93)

 

Surgical procedure

  

0.301

  

0.121

 Laparoscopic

18(0.21)

71(0.26)

 

8(0.21)

40(0.34)

 

 Open

69(0.79)

200(0.74)

 

30(0.79)

76(0.66)

 

Stomy

  

0.006

  

0.033

 Yes

34(0.39)

65(0.24)

 

16(0.42)

28(0.24)

 

 No

53(0.61)

206(0.76)

 

22(0.58)

88(0.76)

 

Location

  

< 0.001

  

< 0.001

 Rectum

21(0.24)

126(0.46)

 

8(0.21)

62(0.53)

 

 Colon

66(0.76)

145(0.54)

 

30(0.79)

54(0.47)

 

Blood transfusion (mL)

  

0.003

  

0.012

 Yes

26(0.30)

42(0.15)

 

14(0.37)

20(0.17)

 

 No

61(0.70)

229(0.85)

 

24(0.63)

96(0.83)

 

WBC (109/L)

6.23(2.26)

6.53(2.31)

0.300

5.76(2.05)

6.80(2.30)

0.027

Lymphocytes

(109/L)

1.50(0.91)

1.32(0.50)

0.110

1.31(0.49)

1.38(0.49)

0.529

Hematocrit

36.14(5.87)

35.23(5.54)

0.631

35.69(6.31)

36.16(5.72)

0.512

Soterocyte

(109/L)

216.25(84.76)

219.47(86.32)

0.875

218.36(78.65)

220.47(80.25)

0.896

International normalized ratio

1.05(0.14)

1.06(0.10)

0.681

1.05(0.08)

1.05(0.15)

0.762

Fibrinogen

(ug/mL)

3.32(1.02)

3.45(1.16)

0.632

3.32(1.12)

3.47(1.03)

0.613

Total bilirubin

(μmol/L)

14.63(8.17)

13.69(8.15)

0.156

13.24(6.54)

13.65(6.67)

0.778

Direct bilirubin(μmol/L)

5.28(3.45)

5.49(3.48)

0.721

4.42(3.25)

4.71(3.18)

0.598

AST (U/L)

23.08(12.65)

20.27(12.87)

0.241

23.26(12.63)

21.08(10.32)

0.268

BUN (mmol/L)

6.43(2.87)

5.87(2.97)

0.367

6.14(3.08)

5.87(2.18)

0.674

Cr(μmol/L)

75.65(21.21)

70.25(21.36)

0.214

78.58(23.64)

70.54(20.97)

0.074

Uric acid

(μmol/L)

315.24(106.54)

301.02(143.26)

0.645

307.87(99.64)

293.57(136.57)

0.524

Serum sodium

(mmol/L)

141.05(3.62)

141.71(3.02)

0.241

141.08(3.65)

141.94(2.87)

0.235

Serum calcium (mmol/L)

2.22(0.19)

2.24(0.18)

0.487

2.22(0.19)

2.25(0.19)

0.412

NLR

  

< 0.001

  

0.002

  ≥ 3.80

39(0.45)

60(0.22)

 

17(0.45)

30(0.26)

 

  < 3.80

48(0.55)

211(0.78)

 

21(0.55)

86(0.74)

 

PLR

  

< 0.001

  

0.045

  ≥ 238.50

37(0.43)

50(0.18)

 

14(0.37)

24(0.21)

 

  < 238.50

50(0.57)

221(0.82)

 

24(0.63)

92(0.79)

 

PNI

  

0.025

  

0.011

  ≥ 48.48

17(0.20)

87(0.32)

 

6(0.16)

44(0.38)

 

  < 48.48

70(0.80)

184(0.68)

 

32(0.84)

72(0.62)

 

LCR

  

< 0.001

  

< 0.001

  ≥ 0.52

6(0.07)

195(0.72)

 

12(0.32)

94(0.81)

 

  < 0.52

81(0.93)

76(0.28)

 

26(0.68)

22(0.19)

 

LMR

  

< 0.001

  

< 0.001

  ≥ 2.46

32(0.37)

201(0.74)

 

16(0.42)

93(0.80)

 

  < 2.46

55(0.63)

70(0.26)

 

22(0.58)

23(0.20)

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