Table 1 Clinical baseline characteristics of BPS/IC patients in the model and validation sets

Age, y

62.5 (56.0–65.0)

63.0 (57.0–66.0)

0.959

BMI

20.0 (17.5–23.0)

21.0 (18.0–22.0)

0.538

Smoking

33 (4.7)

17 (5.6)

0.529

Alcohol consumption

58 (8.2)

23 (7.6)

0.739

Coffee

24 (3.4)

18 (6.0)

0.064

Hypertension

67 (9.5)

33 (10.9)

0.493

Diabetes

361 (51.3)

151 (50.0)

0.710

Number of pregnancies(1/2/3)

657/41/6

290/8/4

0.082

Number of delivery(0/1/2/3)

5/669/28/2

5/289/6/2

0.161

Pausimenia

701 (99.6)

301 (99.7)

0.826

Pelvic inflammation

376 (53.4)

152 (50.3)

0.370

Overactive bladder

661 (93.9)

284 (94.0)

0.928

Anxiety

418 (59.4)

164 (54.3)

0.136

Taking psychotropic drugs

397 (56.4)

153 (50.7)

0.094

Other types of cystitis

15 (2.1)

12 (4.0)

0.097

CD117

6.0 (9.0–12.0)

6.0 (9.0–12.0)

0.668

P2X3R

4.0 (9.0–12.0)

4.0 (9.0–12.0)

0.293

NGF

6.0 (9.0–12.0)

6.0 (9.0–9.0)

0.351

TrkA

6.0 (6.0–8.0)

6.0 (6.0–8.0)

0.821

Urinary leukocyte

4 (0.6)

1 (0.3)

0.624

CRP, mg/L

5.5 (4.6–6.4)

5.5 (5.1–6.4)

0.112

NLR

2.4 (1.9–2.6)

2.4 (1.9–2.6)

0.605

ESR, mm/1 h

7.0 (5.0–8.0)

7.0 (5.0–8.0)

0.920

ALT, U/L

35.0 (25.0–42.0)

31.5 (25.0–39.0)

0.152

AST, U/L

26.0 (24.0–35.0)

34.0 (24.0–35.0)

0.157

Scr, µmol/L

67.0 (58.0–72.0)

67.0 (58.0–72.0)

0.257

Procalcitonin,ug/L

0.4 (0.3–0.5)

0.4 (0.3–0.5)

0.339

Interstitial cystitis score

17.0 (16.0–18.0)

17.0 (16.0–18.0)

0.685

Interstitial cystitis index

14.0 (13.0–15.0)

14.0 (13.0–15.0)

0.755

Questionnaire

19.0 (17.0–21.0)

19.0 (17.0–21.0)

0.065

Interstitial cystitis score (at 3 monthes)

15.0 (5.0–17.0)

15.0 (5.0–17.0)

0.687

Interstitial cystitis index (at 3 monthes)

12.0 (5.0–14.0)

12.0 (5.0–14.0)

0.393

Questionnaire (at 3 monthes)

16.0 (9.0–18.0)

15.0 (9.0–18.0)

0.182

Interstitial cystitis score (at 6 monthes)

15.0 (4.0–17.0)

15.0 (4.0–16.0)

0.324

Interstitial cystitis index (at 6 monthes)

12.0 (4.0–14.0)

11.0 (4.0–14.0)

0.306

Questionnaire (at 6 monthes)

16.0 (4.0–19.0)

15.0 (4.0–18.0)

0.219

Interstitial cystitis score (at 12 monthes)

15.0 (6.0–17.0)

15.0 (7.0–17.0)

0.156

Interstitial cystitis index (at 12 monthes)

12.0 (5.0–14.0)

12.0 (6.0–14.0)

0.310

Questionnaire (at 12 monthes)

16.0 (9.0–18.0)

15.0 (9.0–18.0)

0.204