Table 4 Comparison of CMOST with other microsimulation tools. Screening colonoscopies were performed at 10-year intervals between ages 50 and 75Â years. Results of the microsimulation tools MISCAN, CRC-SPIN, and SimCRC were taken from reference [7]. Numbers indicate percentage reduction or the number of additional colonoscopies or CRC cases as indicated per 1000 individuals. For CMOST, the numbers of the baseline scenario assuming a dwell time of 13Â years (CMOST13) are given; numbers in parenthesis indicate results obtained by using CMOST8 and CMOST19
From: CMOST: an open-source framework for the microsimulation of colorectal cancer screening strategies
| Â | MISCAN | CRC-SPIN | SimCRC | CMOST13 (CMOST8, CMOST19) |
|---|---|---|---|---|
Incidence reduction | 52% | 91% | 82% | 53% (55, 48) |
Mortality reduction | 65% | 92% | 84% | 61% (65, 55) |
Life years gained | 207 | 260 | 327 | 142 (155, 121) |
Screening colonoscopies | 2288 | 2580 | 2574 | 2373 (2304, 2289) |
Surveillance colonoscopies | 1715 | 1341 | 1609 | 1311 (1222, 1251) |
Total colonoscopies | 4002 | 3921 | 4184 | 3600 (3538, 3558) |
CRC cases prevented | 30 | 56 | 54 | 27 (28, 23) |
CRC mortality cases prevented | 19 | 25 | 30 | 12 (13, 10) |
Colonoscopies per case prevented | 135 | 70 | 77 | 132 (124, 155) |
Colonoscopies per LYG | 19 | 15 | 13 | 25 (22, 29) |