Scenario | Reference | Disease | UICC Stage | Mild Therapy | Intense Therapy | Characteristics |
---|---|---|---|---|---|---|
1 | colon cancer | III | OP only | OP + adjuvant 5-FU | survival benefit of intensive therapy | |
2 | [14] | colon cancer | II + III | adjuvant 5 FU | adjuvant 5 FU + Oxaliplatin | no survival benefit |
3 | rectal cancer | I – III | OP only | OP + short-course radiotherapy | no survival benefit | |
Reference | Disease | UICC Stage | Pre-OP Option | Post-OP Option | Characteristics | |
4 | [19] | rectal cancer | II + III | preoperative CRT | postoperative CRT | no survival benefit |